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Merck
CN

B7652

Sigma-Aldrich

Betamethasone 21-phosphate disodium

≥97%

别名:

Betamethasone disodium phosphate, Betamethasone sodium phosphate

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About This Item

经验公式(希尔记法):
C22H28FNa2O8P
CAS号:
分子量:
516.40
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

无菌性

non-sterile

质量水平

检测方案

≥97%

形式

powder

溶解性

water: 50 mg/mL, clear to very slightly hazy, faintly yellow

运输

ambient

储存温度

room temp

SMILES字符串

[Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O

InChI

1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1

InChI key

PLCQGRYPOISRTQ-LWCNAHDDSA-L

基因信息

human ... NR3C1(2908)

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生化/生理作用

Betamethasone is used to treat neonatal respiratory distress syndrome, and psoriasis.

诊断含义

Betamethasone is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. It is applied as a topical cream, ointment, lotion or gel to treat itching (e.g. from eczema). Corticosteroid used to stimulate fetal lung maturation and to decrease the incidence and mortality from intracranial hemorrhage in premature infants

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Repr. 1B - STOT RE 2

靶器官

Liver,Kidney,Endocrine system

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品

分析证书(COA)

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Efficacy results of a 52-week, randomised, double-blind, safety study of a calcipotriol/betamethasone dipropionate two-compound product (Daivobet/Dovobet/Taclonex) in the treatment of psoriasis vulgaris
Kragballe K, et al.
Dermatology (Basel, Switzerland), 213(4), 319-326 (2006)
S-C Liu et al.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 36(2), 121-128 (2011-03-19)
To investigate the necessity of routine application of hyperbaric oxygen therapy for sudden sensorineural hearing loss. DESIGN/SETTING AND PARTICIPANTS: A retrospective chart review looked at 465 patients, with 353 of them receiving pharmacologic treatments alone. Among these patients, 76 underwent
Cardiovascular risk factors after antenatal exposure to betamethasone: 30-year follow-up of a randomised controlled trial
Dalziel SR, et al.
Lancet, 365(9474), 1856-1862 (2005)
George Habib et al.
Clinical rheumatology, 28(1), 85-87 (2008-10-15)
To evaluate the effect of intra-articular steroid injection (IASI) of betamethasone acetate/betamethasone sodium phosphate (Celestone Chronodose) at the knee joint on blood glucose and fructosamine levels in controlled diabetic patients with osteoarthritis of the knee. Controlled diabetic patients (HgA1C <
Tsutomu Ishihara et al.
International journal of pharmaceutics, 385(1-2), 170-175 (2009-10-20)
We have prepared polymeric nanoparticles using a blend of poly(lactic acid) and monomethoxy-polyethyleneglycol(PEG)-polylactide block copolymer along with betamethasone disodium phosphate (BP). Nanoparticles have been screened for anti-inflammatory activity using experimental rat models of inflammation. In the present study, we examined

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