product name
8-溴腺苷-3',5'-环单磷酸, ≥97% (HPLC)
质量水平
检测方案
≥97% (HPLC)
形式
powder
mp
254 °C (dec.) (lit.)
溶解性
aqueous base: soluble, clear
储存温度
−20°C
SMILES字符串
Nc1ncnc2n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c(Br)nc12
InChI
1S/C10H11BrN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
InChI key
DVKQVRZMKBDMDH-UUOKFMHZSA-N
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相关类别
应用
- 处理 H295R细胞，作为 CYP19诱导的阳性对照
- 作为可渗透膜的cAMP类似物，研究其对短路电流(Isc)
- 的影响研究其作为分化诱导剂，分化诱导Whalton′s胶质来源间充质干细胞（WJ-MSC）的潜力
生化/生理作用
特点和优势
其他说明
注意
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How can I solubilize 8-Bromoadenosine 3',5'-cyclic monophosphate (Product No. B5386)?
This product is soluble in alkaline conditions. Sigma routinely tests solubility at 50 mg/ml in 1 N ammonium hydroxide.
How can I store solutions of 8-Bromoadenosine 3',5'-cyclic monophosphate (Product No. B5386)?
The solution should be stored at -20°C, protected from light and will be stable for up to 6 months.
What is the difference between Product No. B5386 and Product No. B7880?
Product No. B5386 is the free acid form of the material, while Product No. B7880 is the sodium salt. The sodium salt aids in the water solubility of the compund. The biological function of the compounds, once dissolved, is identical.
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商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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