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主要文件

安全信息

B1422

Sigma-Aldrich

B-Trisaccharide

别名:

α-D-Gal-(1→3)-(α-L-Fuc-[1→2])-D-Gal, Blood group B trisaccharide

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About This Item

经验公式(希尔记法):
C18H32O15
CAS号:
分子量:
488.44
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:

方案

≥95% (H-NMR)

质量水平

表单

solid

储存温度

2-8°C

SMILES字符串

C[C@@H]1O[C@@H](O[C@H]2C(O)O[C@H](CO)[C@H](O)[C@@H]2O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C18H32O15/c1-4-7(21)10(24)12(26)17(29-4)33-15-14(9(23)6(3-20)30-16(15)28)32-18-13(27)11(25)8(22)5(2-19)31-18/h4-28H,2-3H2,1H3/t4-,5+,6+,7+,8-,9-,10+,11-,12-,13+,14-,15+,16?,17-,18+/m0/s1

InChI key

XNBZPOHDTUWNMW-OUUCXATCSA-N

应用

Blood group B trisaccharide may be used to isolate, identify and characterize blood group trisaccharide specific lectins and ligands such as Langerin and MOA (Marasmius oreades agglutinin).

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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L Rydberg et al.
Sub-cellular biochemistry, 32, 107-125 (1999-07-07)
alpha-Gal terminated saccharides are present on the cell surface both as glycolipids and glycoproteins in all mammals except Old World monkeys and humans. The structural diversity among identified saccharides terminated by this epitope in animal tissues is steadily increasing. The
Brian P Rempel et al.
Glycoconjugate journal, 19(3), 175-180 (2003-06-20)
A novel lectin from the mushroom Marasmius oreades (MOA) has been shown to bind to human blood group B oligosaccharides [1]. In the present work we examine the binding of a series of analogues of the blood group B-trisaccharide, alphaGal(1-3)[alphaFuc(1-2)]betaGal-OR
Ming Tan et al.
PloS one, 4(4), e5058-e5058 (2009-04-02)
Human noroviruses are the major viral pathogens of epidemic acute gastroenteritis. These genetically diverse viruses comprise two major genogroups (GI and GII) and approximately 30 genotypes. Noroviruses recognize human histo-blood group antigens (HBGAs) in a diverse, strain-specific manner. Recently the
Michiel van der Vlist et al.
Immunology and cell biology, 88(4), 410-415 (2010-03-24)
Langerhans cells (LC) are the first dendritic cells (DC) to encounter pathogens entering the body via mucosa or skin. Equipped with pattern recognition receptors (PRR), LC are able to detect and respond to these pathogens. An important PRR, in human
N O Seto et al.
European journal of biochemistry, 234(1), 323-328 (1995-11-15)
A 1034-bp synthetic gene encoding the human blood group B glycosyltransferase, which catalyzes the transfer of galactose from UDP-Gal to Fuc alpha(1-2)Gal beta-OR to give the blood group B determinant Gal alpha(1-3)[Fuc alpha(1-2)]Gal beta-OR (where R is a glycoprotein or

商品

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

O-连接糖蛋白通常是分子量>200kDa的大蛋白。糖基化通常发生在高密度簇上,并可占总量的50-80%。

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