推荐产品
生物来源
yeast
质量水平
检测方案
≥98% (HPLC)
形式
powder
溶解性
1 N NH4OH: 50 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H]3O
InChI
1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI key
LNQVTSROQXJCDD-KQYNXXCUSA-N
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应用
腺苷3′-一磷酸（3′-AMP）是由2′,3′-cAMP水解产生的代谢产物，而后者为金属依赖性磷酸二酯酶家族。3′-AMP可通过A2B受体抑制前肾小球血管平滑肌细胞和肾小球系膜细胞的增殖。 2′,3′-cAMP和3′-AMP代表了基于腺苷的细胞调节的一条新的未探索途径。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Aksorn Saengtienchai et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 214, 28-35 (2018-09-04)
There have been many reports regarding toxic chemicals in birds. Chemicals are mainly metabolized in the liver through phase I oxidation by cytochrome P450 (CYP) and phase II conjugation by conjugated enzymes, such as UDP-glucuronosyltransferase (UGT), sulfotransferase (SULT), glutathione-S-transferase (GST)
Sumit Bansal et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1011, 171-178 (2016-01-17)
Detoxification of lithocholic acid (LCA) to lithocholic acid sulfate (LCA-S) is catalyzed by sulfotransferases, mainly SULT2A1. We developed and validated an ultra-high performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) method to quantify human liver cytosolic-dependent LCA sulfation. Chromatographic separation was achieved
Chun Yuan et al.
Molecular medicine reports, 16(4), 4529-4536 (2017-08-30)
Bone fracture healing is a complex process, which is associated with several factors, including age and osteoporosis. Certain genes and biological processes that may contribute to fracture healing, have been identified following developments in systems biology and molecular biology technologies
Tristan A Smythe et al.
Environmental science & technology, 51(12), 7245-7253 (2017-05-26)
The inhibitory effects of five novel brominated flame retardants, 1,2-bis(2,4,5-tribromophenoxy)ethane (BTBPE), decabromodiphenylethane (DBDPE), 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB), bis(2-ethylhexyl)tetrabromophthalate (BEH-TEBP), and β-tetrabromoethylcyclohexane (β-TBECH), on thyroid hormone deiodinase (DIO) and sulfotransferase (SULT) activity were investigated using human in vitro liver microsomal and cytosolic bioassays.
Jiří Vrba et al.
Metabolites, 10(8) (2020-08-19)
Natural phenolic compounds are known to be metabolized by phase II metabolic reactions. In this study, we examined the in vitro sulfation of the main constituents of silymarin, an herbal remedy produced from the fruits of the milk thistle. The
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