推荐产品
生物来源
bacterial
质量水平
方案
≥95%
表单
powder
溶解性
H2O: 50 mg/mL
储存温度
−20°C
SMILES字符串
[Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O
InChI
1S/C10H16N5O13P3.Mg.2H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;
InChI key
CPGAIACWYFBIFN-UHFFFAOYSA-N
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应用
腺苷5′-三磷酸镁盐已可用于:
- 作为细胞内Ca2+ 保留测定和荧光广域成像分析的补充剂
- 作为甲烷磺酸钾内溶物的一种成分,用于皮层神经元的 体外 电生理研究
- 作为细胞内电位溶液中起作用的组分
生化/生理作用
腺苷5γ-三磷酸腺苷(ATP)是体内能量储存和代谢的中心成分。 ATP应用于许多细胞过程、呼吸、生物合成反应、运动和细胞分裂。ATP是许多激酶的底物,这些激酶参与细胞信号和腺苷酸环化酶(s),产生第二个信使 cAMP。 ATP提供代谢能量来驱动代谢泵。 ATP在一系列酶促反应中充当辅酶。
P2 嘌呤能激动剂;增加 Ca2+-激活的 K+ 通道的活性;ATP-依赖酶系统的底物
警示用语:
Warning
危险声明
危险分类
STOT SE 2
靶器官
Eyes,Central nervous system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
从最新的版本中选择一种:
分析证书(COA)
European journal of pharmacology, 791, 686-695 (2016-10-30)
Pyrazole derivatives were originally suggested as selective blockers of the transient receptor potential cation 3 (TRPC3) and channel. In particular, pyr3 and 10 selectively inhibit TRPC3, whereas pyr2 (BTP2) and 6 inhibit ORAI1. However, their effects on background K+ channel
Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology.
Nature Protocols, 11(1), 61-61 (2016)
Archives of toxicology, 92(9), 2875-2884 (2018-08-08)
Transporter-mediated drug-drug interactions (DDI) may induce adverse clinical events. As drugs of abuse (DOA) are marketed without preclinical safety studies, only very limited information about interplay with membrane transporters are available. Therefore, 13 DOA of various classes were tested for
Spatial separation of mitochondrial calcium uptake and extrusion for energy-efficient mitochondrial calcium signaling in the heart.
Cell reports, 24(12), 3099-3107 (2018)
A subpopulation of striatal neurons mediates Levodopa-induced dyskinesia.
Neuron, 97(4), 787-795 (2018)
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