推荐产品
产品名称
L-天冬氨酸, BioXtra, ≥99% (HPLC)
产品线
BioXtra
质量水平
方案
≥99% (HPLC)
表单
powder
杂质
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
灼烧残渣
≤0.1%
颜色
white to off-white
mp
>300 °C (dec.) (lit.)
溶解性
1 M HCl: 0.5 M, clear, colorless
痕量阴离子
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
痕量阳离子
Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%
SMILES字符串
N[C@@H](CC(O)=O)C(O)=O
InChI
1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI key
CKLJMWTZIZZHCS-REOHCLBHSA-N
基因信息
human ... CA1(759) , CA2(760)
rat ... Grin2a(24409)
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应用
- 代谢组学分析发现作为急性心肌梗死生物标志物的差异代谢物。：研究发现了参与急性心肌梗塞期间代谢途径的关键代谢物，包括L-天门冬氨酸。这项研究加深了人们对心脏病发作时生化变化的了解，有可能产生更好的诊断标志物（Zhou et al., 2024）。
生化/生理作用
L-天冬氨酸是天然蛋白原氨基酸，其可用于细胞培养基的配制，以及蛋白质和多肽合成系统和实验。L-天冬氨酸，一种 NMDA 受体激动剂和非特异性谷氨酸受体激动剂，用于鉴定 NMDA 受体，以及和研究其作用机制。
快速兴奋突触的主要神经递质。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Irena Roci et al.
Cell reports, 26(7), 1691-1700 (2019-02-14)
Alterations in cell-cycle regulation and cellular metabolism are associated with cancer transformation, and enzymes active in the committed cell-cycle phase may represent vulnerabilities of cancer cells. Here, we map metabolic events in the G1 and SG2M phases by combining cell
Johnny Bonnardel et al.
Immunity, 51(4), 638-654 (2019-09-29)
Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific identities of macrophages in their respective niches. Using conditional depletion of liver Kupffer cells, we traced the developmental stages
Ann-Louise Johansson et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(22), 8912-8917 (2013-05-16)
Proton transfer across biological membranes underpins central processes in biological systems, such as energy conservation and transport of ions and molecules. In the membrane proteins involved in these processes, proton transfer takes place through specific pathways connecting the two sides
Guus B Erkens et al.
Nature, 502(7469), 119-123 (2013-10-05)
Excitatory amino acid transporters (EAATs) are secondary transport proteins that mediate the uptake of glutamate and other amino acids. EAATs fulfil an important role in neuronal signal transmission by clearing the excitatory neurotransmitters from the synaptic cleft after depolarization of
Yoshikatsu Kanai et al.
Molecular aspects of medicine, 34(2-3), 108-120 (2013-03-20)
Glutamate transporters play important roles in the termination of excitatory neurotransmission and in providing cells throughout the body with glutamate for metabolic purposes. The high-affinity glutamate transporters EAAC1 (SLC1A1), GLT1 (SLC1A2), GLAST (SLC1A3), EAAT4 (SLC1A6), and EAAT5 (SLC1A7) mediate the
Chromatograms
application for HPLCapplication for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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