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Merck
CN

A7512

Sigma-Aldrich

N-乙酰基-DL-苯丙氨酸 β-萘酯

≥98% (TLC), suitable for ligand binding assays

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About This Item

经验公式(希尔记法):
C21H19NO3
CAS号:
分子量:
333.38
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

产品名称

N-乙酰基-DL-苯丙氨酸 β-萘酯,

方案

≥98% (TLC)

质量水平

表单

powder

技术

ligand binding assay: suitable

颜色

white

储存温度

2-8°C

SMILES字符串

CC(=O)NC(Cc1ccccc1)C(=O)Oc2ccc3ccccc3c2

InChI

1S/C21H19NO3/c1-15(23)22-20(13-16-7-3-2-4-8-16)21(24)25-19-12-11-17-9-5-6-10-18(17)14-19/h2-12,14,20H,13H2,1H3,(H,22,23)

InChI key

BBXRRTJNJCPGBU-UHFFFAOYSA-N

生化/生理作用

N-乙酰基-DL-苯丙氨酸β-萘酯(NAPBNE)是一种发色底物,用于鉴别、区分和表征丝氨酸蛋白酶和肽酶。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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P Collin-Osdoby et al.
Molecular & general genetics : MGG, 243(6), 674-680 (1994-06-15)
Mutations at the apeA locus in Salmonella typhimurium lead to loss of a soluble enzyme ("protease I") that hydrolyzes the chromogenic endoprotease substrate N-acetyl phenylalanine beta-naphthyl ester. We have isolated pseudorevertants of S. typhimurium apeA mutations that have regained the
M A Jongsma et al.
Analytical biochemistry, 212(1), 79-84 (1993-07-01)
An improved, time efficient, visual assay for quantitative determination of proteinase inhibitor activity in protein extracts is reported. Proteinase inhibitor activity of mammalian, bacterial, and fungal serine proteinases can be quantified. The method relies on radial diffusion of proteinase inhibitor
H Y Darani et al.
Parasitology, 115 ( Pt 3), 237-247 (1997-09-23)
A cationic Schistosoma mansoni cercarial antigen was shown to be a serine protease as it was capable of hydrolysing N-acetyl-DL-phenylalanine beta-naphthyl ester (NAPBNE) after precipitation by immunoelectrophoresis, and this reaction was modulated by the serine protease inhibitors phenylmethanesulfonyl fluoride (PMSF)
Miri Aharon et al.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22(8), 847-852 (2002-10-25)
This study investigates the possible involvement of serine proteases in interferon-gamma (IFN-gamma) activity on WISH cells. It was observed that inhibition of (3)H-thymidine incorporation induced by IFN-gamma was abrogated by the serine protease inhibitors Nalpha-tosyl-L-lysyl-chloromethane and soybean trypsin inhibitor, both
H Y Darani et al.
Parasitology, 135(4), 467-472 (2008-01-23)
An enzyme found previously in extracts of adult Schistosoma mansoni worms, that hydrolysed the chromogenic substrate N-acetyl-DL-phenylalanine beta-naphthyl-ester, has here been further investigated and characterized. Evidence that the molecule found in the parasite was antigenically and enzymatically homologous with a

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