所有图片(1)
About This Item
经验公式（希尔记法）:
C13H17NO4 · H2O
CAS号:
分子量:
269.29
Beilstein:
2217900
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
product name
N -乙酰基- L -酪氨酸乙酯 一水合物,
检测方案
≥98%
质量水平
形式
powder
技术
ligand binding assay: suitable
颜色
white
储存温度
−20°C
SMILES字符串
CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O
InChI
1S/C13H17NO4/c1-3-18-13(17)12(14-9(2)15)8-10-4-6-11(16)7-5-10/h4-7,12,16H,3,8H2,1-2H3,(H,14,15)/t12-/m0/s1
InChI key
SKAWDTAMLOJQNK-LBPRGKRZSA-N
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应用
N-乙酰-L-酪氨酸乙酯一水合物已用于：
- 作为底物与1M 1-丙醇用于蛋白包覆微晶法(PCMC)固定化Carlsberg蛋白酶催化的酯交换反应
- 检测蛋白包覆微晶法(PCMC)固定化枯草杆菌蛋白酶Carlsberg的性能
- 作为底物用于枯草杆菌蛋白酶的交联酶晶体(CLEC)的活性筛选
生化/生理作用
N-乙酰基-L-酪氨酸乙酯是 N-末端和 C-末端保护的 L-酪氨酸，其可用于交联研究以及作为检测、分化和/或表征各种蛋白酶和酯酶的底物。
底物
胰凝乳蛋白酶的底物
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Sandra M Arriaga et al.
Clinical biochemistry, 42(9), 919-921 (2009-01-20)
To evaluate if unconjugated bilirubin (UB) inhibits C1 esterase activity. Esterase activity was evaluated by C1-mediated hydrolysis of N-acetyl-L-tyrosine ethyl ester, and binding of UB to C1r and C1s was assessed by dot-blot analysis. UB inhibited C1 enzymatic activity. C1r
Operational stability of subtilisin CLECs in organic solvents in repeated batch and in continuous operation
Fernandes JFA, et al.
Biochemical Engineering Journal, 24(1) (24)
A study of the intermolecular interactions of tolmetin/N-acetyl-L-tyrosine ethyl ester complex.
Tito A, Jimenez-Lopez C, et al.
Spectrochimica Acta Part A: Molecular Spectroscopy, 72, 1000-1006 (2009)
Stability of protein-coated microcrystals in organic solvents
Kreiner M, et al.
Journal of Molecular Catalysis. B, Enzymatic, 33(3-6) (33)
Alicja Janik et al.
Acta crystallographica. Section C, Crystal structure communications, 63(Pt 10), o572-o575 (2007-10-06)
The crystal structure of a protected L-tyrosine, namely N-acetyl-L-tyrosine methyl ester monohydrate, C(12)H(15)NO(4).H(2)O, was determined at both 293 (2) and 123 (2) K. The structure exhibits a network of O-H...O and N-H...O hydrogen bonds, in which the water molecule plays
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