A6751
N -乙酰基- L -酪氨酸乙酯 一水合物
≥98%, suitable for ligand binding assays
别名:
ATEE
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关于此项目
经验公式（希尔记法）:
C13H17NO4 · H2O
化学文摘社编号:
分子量:
269.29
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
NACRES:
NA.26
EC Number:
212-663-5
MDL number:
Beilstein/REAXYS Number:
2217900
产品名称
N -乙酰基- L -酪氨酸乙酯 一水合物,
InChI
1S/C13H17NO4/c1-3-18-13(17)12(14-9(2)15)8-10-4-6-11(16)7-5-10/h4-7,12,16H,3,8H2,1-2H3,(H,14,15)/t12-/m0/s1
InChI key
SKAWDTAMLOJQNK-LBPRGKRZSA-N
SMILES string
CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O
assay
≥98%
form
powder
technique(s)
ligand binding assay: suitable
color
white
storage temp.
−20°C
Quality Level
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Application
N-乙酰-L-酪氨酸乙酯一水合物已用于：
- 作为底物与1M 1-丙醇用于蛋白包覆微晶法(PCMC)固定化Carlsberg蛋白酶催化的酯交换反应
- 检测蛋白包覆微晶法(PCMC)固定化枯草杆菌蛋白酶Carlsberg的性能
- 作为底物用于枯草杆菌蛋白酶的交联酶晶体(CLEC)的活性筛选
Biochem/physiol Actions
N-乙酰基-L-酪氨酸乙酯是 N-末端和 C-末端保护的 L-酪氨酸，其可用于交联研究以及作为检测、分化和/或表征各种蛋白酶和酯酶的底物。
General description
胰凝乳蛋白酶的底物
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Alicja Janik et al.
Acta crystallographica. Section C, Crystal structure communications, 63(Pt 10), o572-o575 (2007-10-06)
The crystal structure of a protected L-tyrosine, namely N-acetyl-L-tyrosine methyl ester monohydrate, C(12)H(15)NO(4).H(2)O, was determined at both 293 (2) and 123 (2) K. The structure exhibits a network of O-H...O and N-H...O hydrogen bonds, in which the water molecule plays
Stability of protein-coated microcrystals in organic solvents
Kreiner M, et al.
Journal of Molecular Catalysis. B, Enzymatic, 33(3-6) (33)
Sandra M Arriaga et al.
Clinical biochemistry, 42(9), 919-921 (2009-01-20)
To evaluate if unconjugated bilirubin (UB) inhibits C1 esterase activity. Esterase activity was evaluated by C1-mediated hydrolysis of N-acetyl-L-tyrosine ethyl ester, and binding of UB to C1r and C1s was assessed by dot-blot analysis. UB inhibited C1 enzymatic activity. C1r
Michaela Kreiner et al.
Biotechnology and bioengineering, 87(1), 24-33 (2004-06-24)
Recently, we reported a new high-activity biocatalyst for use in organic media termed protein-coated microcrystals (PCMC) (Kreiner et al. [2001] Chem Commun 12:1096-1097). These novel particles consist of water-soluble micron-sized crystalline particles coated with the given biocatalyst(s) and are prepared
Operational stability of subtilisin CLECs in organic solvents in repeated batch and in continuous operation
Fernandes JFA, et al.
Biochemical Engineering Journal, 24(1) (24)
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