推荐产品
方案
≥95%
表单
powder
溶解性
0.1 M NaOH: 10 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
NCCN(CCN)\[N+]([O-])=N/O
InChI
1S/C4H13N5O2/c5-1-3-8(4-2-6)9(11)7-10/h10H,1-6H2/b9-7+
InChI key
YNRCBOXEDICOIX-VQHVLOKHSA-N
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应用
3，3-双（氨基乙基）-1-羟基-2-氧代-1-三氮烯已被用作神经元培养的一氧化氮供体补充剂。它也已用作一氧化氮供体，以研究亚硝酸盐处理后蛋白S-亚硝化（SNO）的作用。
已使用3，3-双（氨基乙基）-1-羟基-2-氧代-1-三氮烯深入了解可能有助于尼可地尔在心血管系统中产生有益作用的分子途径。 3，3-双（氨基乙基）-1-羟基-2-氧代-1-三氮烯以速率控制的方式自发释放一氧化氮。
生化/生理作用
3，3-双（氨基乙基）-1-羟基-2-氧代-1-三氮烯是长效一氧化氮供体。它可能在大鼠中表现出伤害性作用。
警示用语：
Danger
危险声明
危险分类
Self-react. C
储存分类代码
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
Natalia Rios et al.
Free radical biology & medicine, 101, 284-295 (2016-09-20)
The specific and sensitive detection of peroxynitrite (ONOO-/ONOOH) in biological systems is a great challenge due to its high reactivity towards several biomolecules. Herein, we validated the advantages of using fluorescein-boronate (Fl-B) as a highly sensitive fluorescent probe for the
Mitochondrial Complex I Reversible S-Nitrosation Improves Bioenergetics and Is Protective in Parkinson's Disease
Milanese C, et al.
Antioxidants & Redox Signaling, 28(1), 44-61 (2018)
Shumin Tan et al.
PLoS pathogens, 9(4), e1003282-e1003282 (2013-04-18)
The ability of Mycobacterium tuberculosis (Mtb) to thrive in its phagosomal niche is critical for its establishment of a chronic infection. This requires that Mtb senses and responds to intraphagosomal signals such as pH. We hypothesized that Mtb would respond
Iris C Vermeulen Windsant et al.
Critical care (London, England), 16(3), R95-R95 (2012-05-26)
The increasing number of reports on the relation between transfusion of stored red blood cells (RBCs) and adverse patient outcome has sparked an intense debate on the benefits and risks of blood transfusions. Meanwhile, the pathophysiological mechanisms underlying this postulated
Katrin F Nickel et al.
PloS one, 8(6), e63504-e63504 (2013-06-21)
A potential role for coagulation factors in pulmonary arterial hypertension has been recently described, but the mechanism of action is currently not known. Here, we investigated the interactions between thrombin and the nitric oxide-cGMP pathway in pulmonary endothelial cells and
商品
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
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