所有图片(1)
About This Item
经验公式（希尔记法）:
C6H15N5O · 2HCl
CAS号:
分子量:
246.14
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
推荐产品
产品名称
L-Argininamide dihydrochloride,
方案
≥98%
质量水平
表单
powder
技术
ligand binding assay: suitable
颜色
white to off-white
储存温度
−20°C
SMILES字符串
Cl.N[C@@H](CCCNC(N)=N)C(N)=O
InChI
1S/C6H15N5O.ClH/c7-4(5(8)12)2-1-3-11-6(9)10;/h4H,1-3,7H2,(H2,8,12)(H4,9,10,11);1H/t4-;/m0./s1
InChI key
BPQLYFCEVVKLLX-WCCKRBBISA-N
相关类别
应用
L-Argininamide dihydrochloride has been used as an additive to compare its effect over L-arg in egg lysozyme refolding studies. It has also been used as a component of substrate stock solution for enzymatic kyotorphin synthesis.
生化/生理作用
L-Argininamide (L-Arm) is a hydrophilic amino acid derivative that is used as a model compound in physicochemical characteristic studies of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - STOT SE 1
靶器官
Eyes
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
G Reid Bishop et al.
Biophysical chemistry, 126(1-3), 165-175 (2006-08-18)
The thermal stability and ligand binding properties of the L-argininamide-binding DNA aptamer (5'-GATCGAAACGTAGCGCCTTCGATC-3') were studied by spectroscopic and calorimetric methods. Differential calorimetric studies showed that the uncomplexed aptamer melted in a two-state reaction with a melting temperature T(m)=50.2+/-0.2 degrees C
Max Keller et al.
Bioorganic & medicinal chemistry, 19(9), 2859-2878 (2011-04-16)
Fluorescently labelled NPY Y(1) receptor (Y(1)R) ligands were synthesized by connecting pyrylium and cyanine dyes with the argininamide-type Y(1)R antagonist core structure by linkers, covering a wide variety in length and chemical nature, attached to the guanidine group. The most
Zhiai Xu et al.
Biosensors & bioelectronics, 26(12), 4733-4738 (2011-07-02)
Aptamers are nucleic acids that can selectively bind to a variety of targets. Aptamers usually undergo conformational transitions from a flexible or disordered structure into a rigid or ordered structure upon target-binding. This study describes a detection method for l-argininamide
Qi Zhang et al.
Science (New York, N.Y.), 311(5761), 653-656 (2006-02-04)
Using a domain elongation strategy, we decoupled internal motions in RNA from overall rotational diffusion. This allowed us to site-specifically resolve a manifold of motional modes in two regulatory RNAs from HIV-1 with the use of nuclear magnetic resonance spin
RNA dynamics by design: biasing ensembles towards the ligand-bound state.
Andrew C Stelzer et al.
Angewandte Chemie (International ed. in English), 49(33), 5731-5733 (2010-06-29)
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