推荐产品
检测方案
≥98%
质量水平
形式
powder
技术
ligand binding assay: suitable
颜色
white to off-white
储存温度
−20°C
SMILES字符串
Cl.N[C@@H](CCCNC(N)=N)C(N)=O
InChI
1S/C6H15N5O.ClH/c7-4(5(8)12)2-1-3-11-6(9)10;/h4H,1-3,7H2,(H2,8,12)(H4,9,10,11);1H/t4-;/m0./s1
InChI key
BPQLYFCEVVKLLX-WCCKRBBISA-N
应用
L-Argininamide dihydrochloride has been used as an additive to compare its effect over L-arg in egg lysozyme refolding studies. It has also been used as a component of substrate stock solution for enzymatic kyotorphin synthesis.
生化/生理作用
L-Argininamide (L-Arm) is a hydrophilic amino acid derivative that is used as a model compound in physicochemical characteristic studies of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - STOT SE 1
靶器官
Eyes
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Razvan Nutiu et al.
Methods (San Diego, Calif.), 37(1), 16-25 (2005-10-04)
Aptamers are single-stranded DNA or RNA molecules with ligand-binding capabilities. Signaling aptamers refer to aptamers or modified aptamers with recordable signal generation ability. Fluorescence-signaling aptamers, in particular, are valuable molecular tools that can be used to establish important techniques or
Hiroaki Ozaki et al.
Bioorganic & medicinal chemistry letters, 16(16), 4381-4384 (2006-06-08)
Fluorescent DNA probes for L-argininamide were developed by a combination of DNA aptamers and fluorophore-quencher pairs. These molecules were synthesized by a combination of pre- and post-synthetic modification methods. The fluorescence-labeled aptamer could detect L-argininamide specifically. The binding affinities were
Stefan Weiss et al.
Bioorganic & medicinal chemistry, 18(17), 6292-6304 (2010-08-07)
N(G)-Acylated argininamides, covering a broad range of lipophilicity (calculated logD values: -1.8-12.5), were synthesized and investigated for NPY Y(1) receptor (Y(1)R) antagonism, Y(1)R affinity and stability in buffer (N(G)-deacylation, yielding BIBP 3226). Broad structural variation of substituents was tolerated. The
Xinhua Guo et al.
Analytical chemistry, 78(20), 7259-7266 (2006-10-14)
The 24-mer DNA aptamer of Harada and Frankel (Harada, K.; Frankel, A. D. EMBO J. 1995, 14, 5798-5811) that binds L-argininamide (L-Arm) was studied by electrospray ionization Fourier transform mass spectrometry (ESI-FTMS). This DNA folds into a stem and loop
Jing Zheng et al.
Analytical chemistry, 83(17), 6586-6592 (2011-07-29)
For successful assay development of an aptamer-based biosensor, various design principles and strategies, including a highly selective molecular recognition element and a novel signal transduction mechanism, have to be engineered together. Herein, we report a new type of aptamer-based sensing
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门