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A3734

1-氮杂坎帕罗酮

Name: 1-氮杂坎帕罗酮
Brand: SIGMA

≥97% (HPLC), glycogen synthase kinase 3β (GSK3β) inhibitor, powder

别名:

9-溴-7，12-二氢-吡啶并[3′，2′:2，3]吖庚因并[4，5-b]吲哚-6（5H）-酮

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关于此项目

经验公式（希尔记法）:

C₁₅H₁₀BrN₃O

化学文摘社编号:

676596-65-9

分子量:

328.16

UNSPSC Code:

12352200

PubChem Substance ID:

329770845

NACRES:

NA.77

MDL number:

MFCD09037522

Assay:

≥97% (HPLC)

Form:

powder

Quality level:

100

Storage condition:

protect from light

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属性

产品名称

1-氮杂坎帕罗酮, ≥97% (HPLC)

Quality Level

100

assay

≥97% (HPLC)

form

powder

storage condition

protect from light

color

gray-brown

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

O=C1CC2=C(NC3=C2C=C(Br)C=C3)C4=C(C=CC=N4)N1

InChI

1S/C15H10BrN3O/c16-8-3-4-11-9(6-8)10-7-13(20)18-12-2-1-5-17-15(12)14(10)19-11/h1-6,19H,7H2,(H,18,20)

InChI key

NTSBZVCEIVPKBJ-UHFFFAOYSA-N

说明

Biochem/physiol Actions

1-氮杂坎帕罗酮（AZP）可刺激β-连环蛋白相关基因的转录。该化合物能诱导β细胞的增殖和复制。

1-Azakenpaullone 是一种细胞渗透性、有效的选择性糖原合酶激酶 3 抑制剂3β （GSK3β）与 CDK 的交叉反应性低 100 倍。1-Azakenpaullone 可与 BIO 和 CHIR99021 一起用作 GSK3 抑制的“金标准”。

1-Azakenpaullone 是一种细胞渗透性、有效的选择性糖原合酶激酶 3β （GSK3β）抑制剂，与 CDK 的交叉反应性低 100 倍。

Disclaimer

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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Glycogen Synthase Kinase 3 (GSK-3) Overview

Glycogen synthase kinase 3 (GSK-3) is a highly conserved family of serine/threonine kinases for over 100 proteins in many pathways. See a list of accepted GSK-3 modulators and related products.

肝醣合成酶激酶3 (GSK-3)概述

肝醣合成酶激酶3 (GSK-3)是一种高度保守的丝氨酸/苏氨酸激酶家族，适于在多种途径中处理100多种蛋白质。查看允许的GSK-3调节剂和相关产品列表。

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A3734-5MG	04061832444505
A3734-1MG	04061826128664