一般描述
免疫球蛋白G(IgG)是一种糖蛋白抗体,其可调节免疫反应,如吞噬作用,也可参与自身免疫疾病的发展。小鼠IgG具有四种不同的同种型,即IgG1、IgG2a、IgG2b和IgG3。IgG1可调节小鼠的补体结合。
当针对纯化的小鼠IgA、IgG和IgM骨髓瘤蛋白进行测试时,山羊抗小鼠IgG(γ-链特异性)-过氧化物酶抗体对小鼠IgG具有特异性。
当针对纯化的小鼠IgA、IgG和IgM骨髓瘤蛋白进行测试时,山羊抗小鼠IgG(γ-链特异性)-过氧化物酶抗体对小鼠IgG具有特异性。
免疫原
纯化小鼠IgG
应用
HRP偶联的山羊抗小鼠γ链特异性用于通过ELISA检测血清和粘膜洗液中针对HIV1的中和抗体。3′3′5,5 四甲基联苯胺(Sigma)可用作开发底物。
山羊抗小鼠IgG(γ-链特异性)过氧化物酶抗体可用于ELISA应用,稀释度为1:3000。
外形
0.01 M磷酸盐缓冲液,pH 7.4,含有1%牛血清白蛋白和防腐剂。
制备说明
采用Wilson,M.B.和Nakane,P.K.在《免疫荧光及相关染色技术》中描述的过碘酸盐法制备(Elsevier/North Holland Biomedical Press,Amsterdam,p215 (1978))。
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警示用语:
Warning
危险分类
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
含少量动物源组分生物产品
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