产品名称
抗-人IgG（Fc特异性）−琼脂糖 山羊抗, affinity isolated antibody, PBS suspension
biological source
goat
conjugate
agarose conjugate
antibody form
affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
form
PBS suspension
species reactivity
human
should not react with
rat, mouse
technique(s)
Ouchterlony double diffusion: suitable
capacity
2 mg/mL, resin binding capacity (human IgG)
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Immunogen
人IgG的Fc片段。
Other Notes
小鼠和大鼠 IgG 吸附的抗体
Physical form
0.01 M 磷酸盐缓冲盐水（pH 7.4）混悬液，含 15 mM 叠氮化钠
Application
使用与琼脂糖珠交联的山羊抗人IgG（Fc特异性）进行免疫沉淀测定。将珠子在1 ml的5%FBS/DMEM中于4℃下稀释2小时。
山羊产生的抗人IgG（Fc特异性）-琼脂糖抗体也已用于从转染的COS细胞上清液中纯化甘丙肽1（Gala1），3Gal取代的P-选择蛋白糖蛋白配体1（PSGL-1）/hIgG1。
羊抗人IgG（Fc特异性）-琼脂糖抗体适用于Ouchterlony双扩散。该抗体还可用于亲和纯化测定。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
人IgG是糖蛋白抗体，含有两条相等的轻链和一对相同的重链。 IgG具有四种不同亚型，范围从IgG1到IgG4。这些抗体可调节机体对过敏和病原性感染的免疫反应。IgG还与补体结合和自身免疫疾病有关。
当针对纯化的人IgA、IgG、IgM、Fc以及κ和λ轻链进行测试时，山羊抗人IgG（Fc特异性）-琼脂糖抗体对人IgG的Fc片段具有特异性。在琼脂糖珠偶联之前，通过Ouchterlony双扩散（ODD）未观察到与小鼠或大鼠IgG的反应性。
当针对纯化的人IgA、IgG、IgM、Fc以及κ和λ轻链进行测试时，山羊抗人IgG（Fc特异性）-琼脂糖抗体对人IgG的Fc片段具有特异性。在琼脂糖珠偶联之前，通过Ouchterlony双扩散（ODD）未观察到与小鼠或大鼠IgG的反应性。
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存储类别
10 - Combustible liquids
wgk
WGK 3
法规信息
常规特殊物品
此项目有
Rebecca J Brown et al.
The Journal of clinical endocrinology and metabolism, 102(6), 1789-1791 (2016-12-03)
Hyperinsulinemia can lead to pathologic ovarian growth and androgen production. A 29-year-old woman developed an autoantibody to the insulin receptor (type B insulin resistance), causing extreme insulin resistance and hyperinsulinemia. Testosterone levels were elevated to the adult male range. Treatment
J L Xu et al.
Immunity, 13(1), 37-45 (2000-08-10)
All rearranging antigen receptor genes have one or two highly diverse complementarity determining regions (CDRs) among the six that typically form the ligand binding surface. We report here that, in the case of antibodies, diversity at one of these regions
Guang Song et al.
Molecular & cellular proteomics : MCP, 17(2), 349-356 (2017-11-17)
Zika virus (ZIKV) and dengue virus (DENV) are closely related flaviviruses that cause widespread, acute febrile illnesses, notably microcephaly for fetuses of infected pregnant women. Detecting the viral cause of these illnesses is paramount to determine risks to patients, counsel
Jining Liu et al.
Xenotransplantation, 10(2), 149-163 (2003-02-18)
Hyperacute organ xenograft rejection can be prevented by removing anti-pig antibodies by extracorporeal absorption prior to transplantation. A novel recombinant absorber of anti-pig antibodies was developed by fusing the cDNA encoding the extracellular part of a mucin-type protein, P-selectin glycoprotein
Manuel Albanese et al.
Cell reports. Medicine, 5(4), 101483-101483 (2024-04-06)
Immune cell phenotyping frequently detects lineage-unrelated receptors. Here, we report that surface receptors can be transferred from primary macrophages to CD4 T cells and identify the Fcγ receptor CD32 as driver and cargo of this trogocytotic transfer. Filamentous CD32+ nanoprotrusions deposit
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