product name
D-精氨酸, ≥98% (TLC)
质量水平
检测方案
≥98% (TLC)
形式
powder
技术
ligand binding assay: suitable
颜色
white to off-white
mp
226 °C (dec.) (lit.)
应用
peptide synthesis
SMILES字符串
N[C@H](CCCNC(N)=N)C(O)=O
InChI
1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1
InChI key
ODKSFYDXXFIFQN-SCSAIBSYSA-N
基因信息
rat ... Ppm1a(24666)
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一般描述
精氨酸(Arg)是一种二元氨基酸，以两种对映异构体形成存在：D-Arg和L-Arg。D-Arg是阳离子型内源氨基酸，存在于中枢神经系统中。
应用
D-精氨酸已用于：
- 作为有机基质，研究不同有机碳源培养的淡水沉积物古菌的代谢多样性
- 研究其在精氨酸酶抑制伪狂犬病毒(PRV)空斑形成中的作用
- 作为色谱分离的参考标准品
生化/生理作用
D-精氨酸是一种半必需氨基酸，用于维持中枢神经系统(CNS)中的细胞死亡。它对CNS中的糖皮质诱导神经毒性具有神经保护作用。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
M Griselda Canteros
Drug discovery today, 19(5), 627-636 (2013-11-21)
In humans, as in other mammals, endogenous glucocorticoids (GCs) are essential for adapting to physiological life stress. They are also crucial for the healthy development of the fetus. However, when the physiological concentrations of GCs increase over a long period
Federica Lazzari et al.
Polymers, 12(4) (2020-04-17)
D- and L-arginine-based polyamidoamino acids, called D- and L-ARGO7, retain the chirality and acid/base properties of the parent -amino acids and show pH-dependent self-structuring in water. The ability of the ARGO7 chiral isomers to selectively interact with chiral biomolecules and/or
Bridget E Fomenky et al.
Scientific reports, 8(1), 14147-14147 (2018-09-22)
This study investigated the effect of supplementing the diet of calves with two direct fed microbials (DFMs) (Saccharomyces cerevisiae boulardii CNCM I-1079 (SCB) and Lactobacillus acidophilus BT1386 (LA)), and an antibiotic growth promoter (ATB). Thirty-two dairy calves were fed a
Hsien-Chi Wang et al.
Biochemical and biophysical research communications, 334(2), 631-637 (2005-07-13)
Pseudorabies virus (PRV) is a member of Alphahepesviruses; it is an enveloped virus with a double-stranded DNA genome. Polyamines (such as spermine and spermidine) are ubiquitous in animal cells and participate in cellular proliferation and differentiation. Previous results of our
Michelle Wehling-Henricks et al.
PloS one, 5(5), e10763-e10763 (2010-05-28)
Duchenne muscular dystrophy (DMD) is the most common, lethal disease of childhood. One of 3500 new-born males suffers from this universally-lethal disease. Other than the use of corticosteroids, little is available to affect the relentless progress of the disease, leading
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