推荐产品
表单
solid
质量水平
颜色
white
溶解性
DMSO: 2 mg/mL
SMILES字符串
NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
InChI
1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
InChI key
LSTPKMWNRWCNLS-UHFFFAOYSA-N
基因信息
human ... GRM1(2911)
rat ... Grm1(24414)
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生化/生理作用
Selective mGluR1 metabotropic glutamate receptor antagonist.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Chiel C de Theije et al.
Endocrinology, 159(1), 519-534 (2017-10-27)
Hypoxemia may contribute to muscle wasting in conditions such as chronic obstructive pulmonary disease. Muscle wasting develops when muscle proteolysis exceeds protein synthesis. Hypoxia induces skeletal muscle atrophy in mice, which can in part be attributed to reduced food intake.
An H Do et al.
Journal of neuroengineering and rehabilitation, 10, 111-111 (2013-12-11)
Excessive reliance on wheelchairs in individuals with tetraplegia or paraplegia due to spinal cord injury (SCI) leads to many medical co-morbidities, such as cardiovascular disease, metabolic derangements, osteoporosis, and pressure ulcers. Treatment of these conditions contributes to the majority of
Christine E King et al.
Journal of neuroengineering and rehabilitation, 10, 77-77 (2013-07-23)
Spinal cord injury (SCI) can leave the affected individuals with paraparesis or paraplegia, thus rendering them unable to ambulate. Since there are currently no restorative treatments for this population, novel approaches such as brain-controlled prostheses have been sought. Our recent
1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors.
R Pellicciari et al.
Journal of medicinal chemistry, 38(19), 3717-3719 (1995-09-15)
Federico Brandalise et al.
PloS one, 7(8), e43417-e43417 (2012-09-01)
In the cerebellar glomerulus, GABAergic synapses formed by Golgi cells regulate excitatory transmission from mossy fibers to granule cells through feed-forward and feedback mechanisms. In acute cerebellar slices, we found that stimulating Golgi cell axons with a train of 10
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