GRM1
glutamate receptor, metabotropic 1
别名:
GPRC1A, MGLU1, MGLUR1, SCAR13
物种:
Human GRM1 (2911), Mouse Grm1 (14816), Rat Grm1 (24414), domestic guinea pig Grm1 (100730891), naked mole-rat Grm1 (101712477), Zebrafish grm1 (100150246), chicken GRM1 (421614), dog GRM1 (484024), Horse GRM1 (100060603), domestic cat GRM1 (101094104) ...展开
UniProtKB ID:
基因ID:
- Human(2911) Summary: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Mouse(14816) glutamate receptor, metabotropic 1
- Rat(24414) glutamate receptor, metabotropic 1
- domestic guinea pig(100730891) glutamate receptor, metabotropic 1
- naked mole-rat(101712477) glutamate receptor, metabotropic 1
- Zebrafish(100150246) glutamate receptor, metabotropic 1
- chicken(421614) glutamate receptor, metabotropic 1
- dog(484024) glutamate receptor, metabotropic 1
- Horse(100060603) glutamate receptor, metabotropic 1
- domestic cat(101094104) glutamate receptor, metabotropic 1
- cow(540485) glutamate receptor, metabotropic 1
- Domestic Rabbit(100356201) glutamate receptor, metabotropic 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
Anti-Metabotropic Glutamate Receptor 1α Antibody, pain, CT, Chemicon®, from rabbit,
物种反应性
human, monkey, rat
应用
immunohistochemistry
western blot
western blot
Anti-GRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Metabotropic Glutamate Receptor 1 Antibody, Chemicon®, from rabbit,
物种反应性
human
应用
immunohistochemistry
Small Molecule - Inhibitor
Small Molecule - Mixed Agonist/Antagonist
货号
说明
物种
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物种
rat, human