A4910
DL-2-Amino-3-phosphonopropionic acid
别名:
3-Phosphono-DL-alanine, AP-3
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关于此项目
经验公式（希尔记法）:
C3H8NO5P
化学文摘社编号:
分子量:
169.07
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
InChI
1S/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)
SMILES string
NC(CP(O)(O)=O)C(O)=O
InChI key
LBTABPSJONFLPO-UHFFFAOYSA-N
form
powder
mp
227-229 °C (lit.)
Quality Level
Gene Information
human ... GRM1(2911), GRM2(2912), GRM3(2913), GRM4(2914), GRM5(2915), GRM6(2916), GRM7(2917), GRM8(2918)
Biochem/physiol Actions
Potent metabotropic glutamate receptor antagonist.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Tine Pokorn et al.
PloS one, 12(9), e0184528-e0184528 (2017-09-09)
Viroids, the smallest known pathogens, unable to encode any proteins, can cause severe diseases in their host plants. One of the proposed mechanisms of their pathogenicity includes silencing the host's genes via viroid-derived small RNAs, which are products of the
T Banno et al.
The Journal of comparative neurology, 402(2), 252-263 (1998-12-09)
The intraventricular administrations of L-glutamate or trans-1-amino-1,3-cyclopentanedicarboxylic acid (t-ACPD), which is an agonist for the metabotropic glutamate receptor, induced conformational changes of the smooth endoplasmic reticulum (SER) to form lamellar bodies, consisting of stacks of flattened cisterns in Purkinje cell
G Pellegri et al.
The European journal of neuroscience, 10(1), 272-280 (1998-09-30)
In view of the neurotrophic effect of vasoactive intestinal peptide (VIP), the regulation of brain-derived neurotrophic factor (BDNF) expression by VIP and the related peptide pituitary adenylate cyclase-activating polypeptide (PACAP) was analysed by Northern blot in primary cultures of cortical
Tao Wang et al.
Molecular cancer research : MCR, 17(2), 398-408 (2018-09-30)
The αvβ3 integrin is involved in various physiologic and pathologic processes such as wound healing, angiogenesis, tumor growth, and metastasis. The impact of αvβ3 integrin on the radiosensitivity of prostate cancer cells and the molecular mechanism controlling cell survival in
Carlos Tejeda-Guzmán et al.
The Journal of experimental biology, 221(Pt 6) (2018-01-26)
Membrane transporters and sequestration mechanisms concentrate metal ions differentially into discrete subcellular microenvironments for use in protein cofactors, signalling, storage or excretion. Here we identify zinc storage granules as the insect's major zinc reservoir in principal Malpighian tubule epithelial cells
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