产品名称
Nα-乙酰基-L-赖氨酸,
assay
≥98% (TLC)
Quality Level
form
powder
technique(s)
ligand binding assay: suitable
color
colorless to white
mp
256-258 °C (dec.) (lit.)
storage temp.
−20°C
SMILES string
CC(=O)N[C@@H](CCCCN)C(O)=O
InChI
1S/C8H16N2O3/c1-6(11)10-7(8(12)13)4-2-3-5-9/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13)/t7-/m0/s1
InChI key
VEYYWZRYIYDQJM-ZETCQYMHSA-N
Application
Nα-乙酰基L-赖氨酸已作为赖氨酰氧化酶的底物,用于合成真正的α-氨基己二酸半醛 (AAS)-p-氨基苯甲酸 (ABA)。它可用于合成4,4′-亚甲基二苯基二异氰酸酯 (MDI) 的氨基酸加成物。
Biochem/physiol Actions
Nα-乙酰基-L-赖氨酸是蛋白质原型α氨基酸L-赖氨酸的一种生物学上可获得的N-末端封端形式。Nα-乙酰基-L-赖氨酸是用于研究和表征赖氨酰氧化酶的一种底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Wenhui Ren et al.
Scientific reports, 7, 39986-39986 (2017-01-04)
As members of bromodomain and extra-terminal motif protein family, bromodomain-containing proteins regulate a wide range of biological processes including protein scaffolding, mitosis, cell cycle progression and transcriptional regulation. The function of these bromodomain proteins (Brds) in innate immune response has
Jing Bi et al.
Emerging microbes & infections, 7(1), 108-108 (2018-06-15)
The DosR regulon is believed to be a key factor in latency adaptation of Mycobacterium tuberculosis and is strongly induced by multiple stresses, including hypoxia. Previous studies have revealed reversible acetylation of the conserved core DNA-binding lysine residue 182 (K182)
Yael Belo et al.
Biochimica et biophysica acta. General subjects, 1863(9), 1343-1350 (2019-06-07)
The signal transducer and activator of transcription 3 (STAT3) protein is activated by phosphorylation of a specific tyrosine residue (Tyr705) in response to various extracellular signals. STAT3 activity was also found to be regulated by acetylation of Lys685. However, the
Tenley C Archer et al.
Cancer cell, 34(3), 396-410 (2018-09-12)
There is a pressing need to identify therapeutic targets in tumors with low mutation rates such as the malignant pediatric brain tumor medulloblastoma. To address this challenge, we quantitatively profiled global proteomes and phospho-proteomes of 45 medulloblastoma samples. Integrated analyses
Sheng-Jun Fan et al.
Cell death & disease, 9(6), 655-655 (2018-05-31)
Alzheimer's disease (AD) is a dreadful neurodegenerative disease that leads to severe impairment of cognitive function, leading to a drastic decline in the quality of life. The primary pathological features of AD include senile plaques (SPs) and intracellular neurofibrillary tangles
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A2010-500MG | 04061832420998 |
| A2010-1G | 04061833343326 |
| A2010-100MG | 04061833343319 |
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