推荐产品
生物来源
rabbit
质量水平
偶联物
alkaline phosphatase conjugate
抗体形式
affinity isolated antibody
抗体产品类型
secondary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
baboon, monkey, marmoset
技术
direct ELISA: 1:40,000
dot blot: 1:60,000 (direct chemiluminescence assay)
运输
wet ice
储存温度
2-8°C
靶向翻译后修饰
unmodified
一般描述
IgG (immunoglobulin G) antibody subtype is a predominant serum immunoglobulin of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. IgG is found in four subclasses IgG1, IgG2, IgG3 and IgG4. IgG has a monomeric structure.
IgGs are glycoprotein antibodies that modulate several immune responses. Serum IgG levels of rhesus monkeys are comparable to that of men, hence these monkeys are often used as models for studying immunological disorders. Thus, anti-monkey IgGs can be useful tools for the detection and localization of monkey IgGs. Anti-Monkey IgG (whole molecule)-Alkaline Phosphatase antibody binds to monkey, baboon and marmoset IgGs.
免疫原
Purified monkey IgG (rhesus)
应用
Alkaline phosphatase-conjugated rabbit anti-monkey IgG antibody has been used as a secondary antibody in enzyme linked immunsorbent assay (ELISA) to detect the level of IgG in serum from treated marmoset monkeys. It has also been used for western blot analysis of to identify maternal IgGs in serum from Rhesus monkeys after lentiviral gene transfer.
生化/生理作用
IgG antibody participates in complement fixation and opsonization.
外形
Solution in 0.05 M Tris, pH 8.0, containing 1% bovine serum albumin, 1 mM MgCl2 and 15 mM sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
含少量动物源组分生物产品
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
S J Challacombe et al.
Immunology, 36(2), 331-338 (1979-02-01)
Rhesus monkey IgG, IgA and IgM were purified from pooled normal serum and labelled with 125I. Four monkeys were injected intravenously with approximately 50 microgram of each purified immunoglobulin containing between 25 muCi and 50 muCi of 125I. Iodination was
Stefano Colloca et al.
Science translational medicine, 4(115), 115ra2-115ra2 (2012-01-06)
Replication-defective adenovirus vectors based on human serotype 5 (Ad5) induce protective immune responses against diverse pathogens and cancer in animal models, as well as elicit robust and sustained cellular immunity in humans. However, most humans have neutralizing antibodies to Ad5
L Boon et al.
Journal of immunology (Baltimore, Md. : 1950), 167(5), 2942-2949 (2001-08-18)
Inhibition of CD40-CD40 ligand interaction is a potentially effective approach for treatment of autoimmune diseases, such as multiple sclerosis. We have investigated this concept with a chimeric antagonist anti-human CD40 mAb (ch5D12) in the marmoset monkey experimental autoimmune encephalomyelitis (EAE)
Alexander D Douglas et al.
Nature communications, 10(1), 1953-1953 (2019-04-28)
Malaria vaccine design and prioritization has been hindered by the lack of a mechanistic correlate of protection. We previously demonstrated a strong association between protection and merozoite-neutralizing antibody responses following vaccination of non-human primates against Plasmodium falciparum reticulocyte binding protein
IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4
Avery DT, et al.
Journal of Immunology, 181(3), 1767-1779 (2008)
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