跳转至内容
Merck
CN

A1651

Sigma-Aldrich

腺苷 3′-磷酸 5′-磷酰硫酸 锂盐 水合物

≥60%

别名:

3′-膦酸腺苷 5′-磷酰硫酸 锂盐, APPS, PAPS, 活性硫酸盐

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C10H15N5O13P2S · xLi+ · yH2O
分子量:
507.26 (free acid basis)
Beilstein:
8181191
MDL编号:
UNSPSC代码:
41106305
eCl@ss:
32160414
NACRES:
NA.51

表单

powder

质量水平

浓度

≥60%

运输

dry ice

储存温度

−70°C

SMILES字符串

[Li+].[Li+].[Li+].[Li+].[P](=O)([O-])([O-])O[C@@H]1[C@H](O[C@H]([C@@H]1O)[n]2c3ncnc(c3nc2)N)CO[P](=O)([O-])O[S](=O)(=O)[O-].O

InChI

1S/C10H15N5O13P2S.4Li.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(27-29(17,18)19)4(26-10)1-25-30(20,21)28-31(22,23)24;;;;;/h2-4,6-7,10,16H,1H2,(H,20,21)(H2,11,12,13)(H2,17,18,19)(H,22,23,24);;;;;1H2/q;4*+1;/p-4/t4-,6-,7-,10-;;;;;/m1...../s1

InChI key

UGODCLHJOJPPHP-AZGWGOJFSA-J

正在寻找类似产品? 访问 产品对比指南

应用

3′-磷酸腺苷5′-磷硫酸盐(PAPS)用作磺基转移酶的体内磺化通用硫酸盐供体。 PAPS用于聚糖的硫酸化。 PAPS还用于研究它其生物转运体的分布和功能。
腺苷3′-磷酸5′-磷酸锂盐被用来克隆和研究哺乳动物锂敏感二磷酸3′-核酸酶,以及它如何被肌醇1,4-二磷酸抑制。腺苷3′-磷酸5′-磷酸锂盐同样用于评估高尔基居民PAP-特异性3′-磷酸酶偶联磺基转移酶分析。

质量

主要杂质为腺苷 3′,5′-二磷酸盐、硫酸盐以及氨取代产物。

注意

当暴露在室温条件,会发生快速降解:在37℃条件下每天降解高达17%。我们是干冰运输,尽可能减少运输过程中的降解。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

J P Horwitz et al.
Biochimica et biophysica acta, 480(2), 376-381 (1977-02-09)
A practical synthesis of 3'-phosphoadenosine 5'-phosphosulfate (IV) in yields of 68-72% from adenosine 2',3'-cyclic phosphate 5'-phosphate (II) is described. Reaction of II with triethylamine-N-sulfonic acid affords adenosine 2',3'-cyclic phosphate 5'-phosphosulfate (III) which, on treatment with ribonuclease-T2, provides IV. Spleen phosphodiesterase
Cooper, B.P. and Baumgarten, F.E.
Zeitschrift fur Naturforschung, 159 (1980)
Emanuel Smeds et al.
Glycobiology, 20(10), 1274-1282 (2010-06-18)
The signaling of various molecules involved in development and regulation of cell growth are regulated by heparan sulfate (HS). Specific binding of HS to ligand proteins depends on the HS sulfation pattern, where the spacing and number of O-sulfate groups
Xianxuan Zhou et al.
Glycobiology, 21(6), 771-780 (2011-01-13)
Heparan sulfate (HS) belongs to a major class of glycans that perform central physiological functions. Heparin is a specialized form of HS and is a clinically used anticoagulant drug. Heparin is a natural product isolated from pig intestine. There is
Saveria Pastore et al.
The Journal of investigative dermatology, 127(3), 660-667 (2006-10-14)
ATP is abundantly released from stressed or damaged cells in response to mechanical stimulation, bacteria, or noxious agents. In this study, we have investigated the possible involvement of P2 receptors (receptor for extracellular nucleotides) in the expression and release of

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门