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Merck
CN

A5845

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin

≥95% (HPLC), powder

别名:

Ac-LEHD-AFC

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关于此项目

经验公式（希尔记法）:
C33H38O11N7F3
分子量:
765.69
NACRES:
NA.32
PubChem Substance ID:
329770876
UNSPSC Code:
12352209
MDL number:
MFCD01862610

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产品名称

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder

InChI

1S/C33H38F3N7O11/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48)/t21-,22-,23-,24-/m0/s1

SMILES string

CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2

InChI key

HULKIXRFKRCRHD-ZJZGAYNASA-N

assay

≥95% (HPLC)

form

powder

color

white

solubility

DMSO/DMF: 20 mM

storage temp.

−20°C

Quality Level

200

Gene Information

human ... CARD9(64170), CASP9(842)
mouse ... CARD9(332579), CASP9(12371)
rat ... CARD9(64171), CASP9(58918)

Application

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin has been used to assay caspase 9 activity using a substrate-based fluorimetric detection assay

General description

Amino acid derivatives of 7-amido-4-trifluoromethylcoumarin (AFC) are blue in fluorescence microscopy.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCH2235
SLBX1062
SLBW4669
SLBR4989V
SLBQ2014V

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