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Merck
CN
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文件

安全信息

A5845

Sigma-Aldrich

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin

≥95% (HPLC), powder

别名:

Ac-LEHD-AFC

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About This Item

经验公式（希尔记法）:
C33H38O11N7F3
分子量:
765.69
MDL编号:
MFCD01862610
UNSPSC代码:
12352209
PubChem化学物质编号:
329770876
NACRES:
NA.32

质量水平

200

检测方案

≥95% (HPLC)

形式

powder

颜色

white

溶解性

DMSO/DMF: 20 mM

储存温度

−20°C

SMILES字符串

CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2

InChI

1S/C33H38F3N7O11/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48)/t21-,22-,23-,24-/m0/s1

InChI key

HULKIXRFKRCRHD-ZJZGAYNASA-N

基因信息

human ... CARD9(64170) , CASP9(842)
mouse ... CARD9(332579) , CASP9(12371)
rat ... CARD9(64171) , CASP9(58918)

相关类别

Amino Acid Sequence

NAc-Leu-Glu-His-Asp-AFC

一般描述

Amino acid derivatives of 7-amido-4-trifluoromethylcoumarin (AFC) are blue in fluorescence microscopy.

应用

N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin has been used to assay caspase 9 activity using a substrate-based fluorimetric detection assay

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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