A5845
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin
≥95% (HPLC), powder
别名:
Ac-LEHD-AFC
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选择规格
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关于此项目
经验公式（希尔记法）:
C33H38O11N7F3
分子量:
765.69
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white
solubility
DMSO/DMF: 20 mM
storage temp.
−20°C
SMILES string
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(O)=O)C(=O)Nc2ccc3c(OC(=O)C=C3C(F)(F)F)c2
InChI
1S/C33H38F3N7O11/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48)/t21-,22-,23-,24-/m0/s1
InChI key
HULKIXRFKRCRHD-ZJZGAYNASA-N
Gene Information
human ... CARD9(64170), CASP9(842)
mouse ... CARD9(332579), CASP9(12371)
rat ... CARD9(64171), CASP9(58918)
General description
Amino acid derivatives of 7-amido-4-trifluoromethylcoumarin (AFC) are blue in fluorescence microscopy.
Application
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin has been used to assay caspase 9 activity using a substrate-based fluorimetric detection assay
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)