CASP9
caspase 9, apoptosis-related cysteine peptidase
别名:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
物种:
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), domestic cat CASP9 (768260), naked mole-rat Casp9 (101702898), cow CASP9 (100140945), Horse CASP9 (100054331), dog CASP9 (487432), chicken CASP9 (426970), sheep CASP9 (101110953) ...展开
UniProtKB ID:
基因ID:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
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Antibodies
货号
说明
物种反应性
应用
Anti-CASP9 (Cleaved-Asp330), C-Terminal antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase 9 antibody,Mouse monoclonal, clone CAS9, purified from hybridoma cell culture,
物种反应性
human
应用
ELISA
microarray
western blot
microarray
western blot
Anti-Caspase-9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Caspase 9 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase 9 Antibody, clone 96-2-22, clone 96-2-22, Upstate®, from mouse,
物种反应性
human
应用
western blot
Small Molecule - Inhibitor
Kits
货号
说明
物种
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
物种
human
Caspase 9 Colorimetric Activity Assay Kit, LEHD, Caspase-9 Colorimetric Activity Assay Kits provide a simple & convenient means for assaying the activity of caspases that recognize the LEHD.,
物种
human
Proteins
货号
说明
物种
Caspase 9 human, ≥90% (SDS-PAGE), recombinant, expressed in E. coli (C-terminal histidine-tagged), buffered aqueous solution, >2,000 units/mg protein,
物种
human
esiRNA
Small Molecule - Substrate
货号
说明
物种
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
物种
mouse, rat, human