所有图片(1)
别名:
(E)-4-羟基-3-甲基-2-烯基二磷酸酯 锂盐, 1-羟基-2-甲基-2-(E)-丁烯基-4-二磷酸酯, HDMAPP, HMBPP, HO-DMAPP
经验公式（希尔记法）:
C5H12O8P2 · xLi+
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质量水平
检测方案
≥95.0% (TLC)
形式
solid
储存温度
−20°C
InChI
1S/C5H12O8P2/c1-5(4-6)2-3-12-15(10,11)13-14(7,8)9/h2,6H,3-4H2,1H3,(H,10,11)(H2,7,8,9)/p-3
InChI key
MDSIZRKJVDMQOQ-UHFFFAOYSA-K
相关类别
生化/生理作用
HMB-PP是类异戊二烯生物合成的非甲羟戊酸途径（MEP途径）的一种中间体；它被证明是一种有效的γδT细胞激活剂。
包装
无底玻璃瓶。内含物装在插入的融合锥内。
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
M Hintz et al.
FEBS letters, 509(2), 317-322 (2001-12-14)
The gcpE and lytB gene products control the terminal steps of isoprenoid biosynthesis via the 2-C-methyl-D-erythritol 4-phosphate pathway in Escherichia coli. In lytB-deficient mutants, a highly immunogenic compound accumulates significantly, compared to wild-type E. coli, but is apparently absent in
Matthias Eberl et al.
FEBS letters, 544(1-3), 4-10 (2003-06-05)
Human Vgamma9/Vdelta2 T cells play a crucial role in the immune response to microbial pathogens, yet their unconventional reactivity towards non-peptide antigens has been enigmatic until recently. The break-through in identification of the specific activator was only possible due to
The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants.
M Rohmer
Natural product reports, 16(5), 565-574 (1999-12-10)
Felix Rohdich et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(3), 1158-1163 (2002-01-31)
Isopentenyl diphosphate and dimethylallyl diphosphate serve as the universal precursors for the biosynthesis of terpenes. Although their biosynthesis by means of mevalonate has been studied in detail, a second biosynthetic pathway for their formation by means of 1-deoxy-D-xylulose 5-phosphate has
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