93851
DL-o-Tyrosine
≥96.0% (NT), suitable for HPLC
别名:
(±)-2-Amino-3-(2-hydroxyphenyl)propionic acid, 3-(2-Hydroxyphenyl)-DL-alanine
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关于此项目
经验公式（希尔记法）:
C9H11NO3
化学文摘社编号:
分子量:
181.19
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
219-134-8
MDL number:
Beilstein/REAXYS Number:
2805789
产品名称
DL-o-Tyrosine, ≥96.0% (NT)
InChI key
WRFPVMFCRNYQNR-UHFFFAOYSA-N
InChI
1S/C9H11NO3/c10-7(9(12)13)5-6-3-1-2-4-8(6)11/h1-4,7,11H,5,10H2,(H,12,13)
SMILES string
NC(Cc1ccccc1O)C(O)=O
assay
≥96.0% (NT)
form
powder
technique(s)
HPLC: suitable
color
white to faint brown
mp
~260 °C (dec.)
application(s)
peptide synthesis
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Biochem/physiol Actions
ortho-Tyrosine (o-Tyrosine), an isomer of standard p-tyrosine, is a phenylalanine oxidation product used as an amino acid oxidation stress marker in analytical procedures such as HPLC and LC-ESI-MS/MS.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Measurement of o- and m-tyrosine as markers of oxidative damage in motor neuron disease.
A Poljak et al.
Redox report : communications in free radical research, 5(2-3), 137-140 (2000-08-12)
P Dandona et al.
Circulation, 101(2), 122-124 (2000-01-19)
The purpose of this study was to test whether carvedilol has an antioxidant effect in humans in vivo. We administered 3.125 mg of carvedilol twice daily to normal subjects for 1 week. ROS generation by polymorphonuclear leukocytes and mononuclear cells
Rachael A Dunlop et al.
The Biochemical journal, 435(1), 207-216 (2011-01-08)
Cellular deposits of oxidized and aggregated proteins are hallmarks of a variety of age-related disorders, but whether such proteins contribute to pathology is not well understood. We previously reported that oxidized proteins form lipofuscin/ceroid-like bodies with a lysosomal-type distribution and
C H Magsino et al.
Metabolism: clinical and experimental, 49(6), 799-803 (2000-07-06)
We have examined the effect of short-term triiodothyronine (T3) administration on reactive oxygen species (ROS) generation by leukocytes in 9 euthyroid subjects. At a dose of 60 microg/d orally for 7 days, T3 induced a significant increase in ROS generation
Gergõ A Molnár et al.
Kidney international, 68(5), 2281-2287 (2005-10-14)
Phenylalanine is converted to para- and ortho-tyrosine by hydroxyl free radical, or to para-tyrosine by the phenylalanine hydroxylase enzyme. The aim of this study was to measure para- and ortho-tyrosine in the urine and plasma of patients with chronic renal
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