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Merck
CN

90101

Ampliflu Red

suitable for fluorescence, ≥98.0% (HPLC)

别名:

10-乙酰基-3,7-二羟基吩噁嗪

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经验公式(希尔记法):
C14H11NO4
化学文摘社编号:
分子量:
257.24
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
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产品名称

Ampliflu Red, suitable for fluorescence, ≥98.0% (HPLC)

InChI key

PKYCWFICOKSIHZ-UHFFFAOYSA-N

SMILES string

CC(=O)N1c2ccc(O)cc2Oc3cc(O)ccc13

InChI

1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3

assay

≥98.0% (HPLC)

form

powder

Quality Level

mol wt

257.24 g/mol

concentration

90-100 % (w/w) (Ampliflu Red)

color

slightly brown-red
white to slightly brown

solubility

water: slightly soluble at 20 °C

fluorescence

λex 571 nm; λem 585 nm in DMSO

suitability

suitable for fluorescence

storage temp.

2-8°C

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Application

Ampliflu Red 已被用于研究帕金森病相关的线粒体异常和氧化应激。Ampliflu Red 检测适合作为 hTPO(人甲状腺过氧化物酶)活性抑制的替代指标检测。磷脂酶 D 是一种重要的细胞过程成分,使用 Ampliflu Red(10-乙酰-3,7-二羟基苯恶嗪)测定其活性。Ampliflu Red 用于以下应用:
  • 炎症介质的定量
  • 测定游离和酯化的胆固醇含量
  • 评价化合物作为 GABA-AT 化合物的底物

Legal Information

Ampliflu is a trademark of Sigma-Aldrich Co. LLC

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Chemistry (Weinheim an der Bergstrasse, Germany), 24(63), 16865-16872 (2018-08-29)
Cetyl-trimethylammonium bromide (CTAB) is a widely used cationic surfactant that is biodegradable in nature. CTAB biodegradation requires hydroxylation in the first step, which is rate-limiting and crucial for solubility in water. In this study, the OmniChange multi-site mutagenesis method was
Thais Soprani Ayala et al.
Scientific reports, 9(1), 11447-11447 (2019-08-09)
Macrophages may be a crucial aspect of diabetic complications associated with the inflammatory response. In this study, we examined how hyperglycaemia, a common aspect of diabetes, modulates bone marrow-derived macrophages (BMDMs) under an inflammatory stimulus. To perform this study, BMDMs
Kazuo Sugiyama et al.
PloS one, 9(4), e94460-e94460 (2014-04-11)
Most of experiments for HCV infection have been done using lytic infection systems, in which HCV-infected cells inevitably die. Here, to elucidate metabolic alteration in HCV-infected cells in a more stable condition, we established an HCV-persistently-infected cell line, designated as
Maria Luisa Di Paolo et al.
Journal of enzyme inhibition and medicinal chemistry, 34(1), 740-752 (2019-03-05)
Fourteen polyamine analogues, asymmetric or symmetric substituted spermine (1-9) or methoctramine (10-14) analogues, were evaluated as potential inhibitors or substrates of two enzymes of the polyamine catabolic pathway, spermine oxidase (SMOX) and acetylpolyamine oxidase (PAOX). Compound 2 turned out to
Barae Jomaa et al.
ALTEX, 32(3), 191-200 (2015-03-31)
A simple and rapid luminometric assay for the detection of chemical inhibitors of human thyroid peroxidase (hTPO) activity was developed and validated with 10 model compounds. hTPO was derived from the human thyroid follicular cell line Nthy-ori 3-1 and its

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