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Merck
CN

88315

Sigma-Aldrich

Thesit®

for membrane research

别名:

四聚乙二醇单月桂醚, 聚乙二醇 (400) 单月桂酸酯, 羟基聚乙氧基十二烷, 聚乙二醇月桂基醚, 聚多卡醇, 聚桂醇

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About This Item

线性分子式:
HO(CH2CH2O)n(CH2)11CH3
CAS号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.21

等级

for membrane research

质量水平

描述

non-ionic

表单

solid

分子量

average mol wt 583

杂质

≤1 ppm peroxides (as H2O2)

CMC

0.1 mM (20-25°C)

SMILES字符串

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

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应用

Thesit加入反应缓冲液可降低背景沉淀。
推荐替代牛脑G蛋白制备所用的Lubrol。

生化/生理作用

Thesit/聚多卡醇具有体外和体内的抗血管生成作用。这种硬化剂主要用于硬化疗法。

法律信息

Thesit is a registered trademark of Desitin Arzneimittel GmbH

象形图

Exclamation markEnvironment

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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访问文档库

K Parsi et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 41(2), 267-277 (2010-12-25)
To investigate the in vitro effects of detergent sclerosants sodium tetradecyl sulphate (STS) and polidocanol (POL) on clot formation and lysis. clot kinetics were assessed in whole blood by thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®). Fibrinogen was measured by the
Measuring protein binding to F-actin by co-sedimentation
Heier JA, et al.
Journal of Visualized Experiments, e55613-e55613 (2017)
Synthesis and use of biotinylated beta gamma complexes prepared from bovine brain G proteins.
J Dingus et al.
Methods in enzymology, 237, 457-471 (1994-01-01)
Polidocanol (Lauromacrogol 400) has anti-angiogenic effects in vitro and in vivo
Doganci S, et al.
European Review for Medical and Pharmacological Sciences, 20(7), 1384-1389 (2016)
Otte Brosjö et al.
Acta orthopaedica, 84(5), 502-505 (2013-11-01)
Recent data suggest that percutaneous sclerotherapy is a safe alternative to surgery for treatment of aneurysmal bone cysts (ABCs). We present our experience of this method. We retrospectively analyzed data from 38 consecutive patients treated with repeated injections of polidocanol.

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