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Merck
CN

84110

Sucrose monolaurate

BioXtra, ≥97.0% (TLC)

别名:

n-Dodecanoylsucrose, Lauric acid sucrose ester, Sucrose monododecanoate

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关于此项目

经验公式（希尔记法）:
C24H44O12
分子量:
524.60
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
57652988
EC Number:
246-873-3
Beilstein/REAXYS Number:
65819
MDL number:
MFCD00077947

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InChI key

KGUHOFWIXKIURA-VQXBOQCVSA-N

InChI

1S/C24H44O12/c1-2-3-4-5-6-7-8-9-10-11-17(27)33-13-16-18(28)20(30)21(31)23(34-16)36-24(14-26)22(32)19(29)15(12-25)35-24/h15-16,18-23,25-26,28-32H,2-14H2,1H3/t15-,16-,18-,19-,20+,21-,22+,23-,24+/m1/s1

SMILES string

CCCCCCCCCCCC(=O)OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

description

non-ionic

product line

BioXtra

assay

≥97.0% (TLC)

form

powder

mol wt

524.60 g/mol

impurities

≤3% water

CMC

0.3

cation traces

Ca: ≤50 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤1000 mg/kg, Mg: ≤10 mg/kg, Mn: ≤5 mg/kg, Na: ≤500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤10 mg/kg

storage temp.

2-8°C

Quality Level

100

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相关类别

General description

Sucrose monolaurate is a non-ionic detergent and a carbohydrate fatty acid monoester. It is generally used for the solubilization of membrane proteins.

Application

Sucrose monolaurate has been used as an antimicrobial agent. It has also been used as a constituent of lysis buffer to homogenize placental tissues for determining serine palmitoyltransferase (SPT) activity.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM9371
BCCM8605
BCCM5973
BCCK2131
BCCH6351

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Mitsugu Shimobayashi et al.
Molecular biology of the cell, 24(6), 870-881 (2013-02-01)
The evolutionarily conserved Orm1 and Orm2 proteins mediate sphingolipid homeostasis. However, the homologous Orm proteins and the signaling pathways modulating their phosphorylation and function are incompletely characterized. Here we demonstrate that inhibition of nutrient-sensitive target of rapamycin complex 1 (TORC1)
Angéla Szuts et al.
International journal of pharmaceutics, 410(1-2), 107-110 (2011-03-23)
This study focused on an investigation of the applicability of sucrose laurate as surfactant in solid dispersions. Although this surfactant has a US Drug Master File, it has not been used so far in internal pharmaceutical products. High drug-loaded solid
Shan He et al.
PloS one, 14(5), e0216816-e0216816 (2019-05-31)
The high heat and mass transfer, and controlled mechanoenergy, in angled vortex fluidics has been applied in chemical and material sciences and allied fields, but its utility in food processing remains largely unexplored. Herein we report three models of food
Non-reducing trisaccharide fatty acid monoesters: novel detergents in membrane biochemistry
Perez-Victoria I, et al.
Biochimica et Biophysica Acta - Biomembranes, 1808(3), 717-726 (2011)
Levente Kürti et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(3), 445-454 (2012-01-26)
Sucrose esters are effective solubilizers and there is an interest to use them as pharmaceutical excipients for nasal drug delivery. We have determined for the first time the non-toxic doses of laurate and myristate sucrose esters by four independent methods
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