推荐产品
质量水平
方案
≥98.0% (HPLC)
表单
powder
技术
HPLC: suitable
颜色
faint beige to light beige
white to light yellow
SMILES字符串
Cc1ncc(COP(O)(O)=O)c(CN)c1O
InChI
1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChI key
ZMJGSOSNSPKHNH-UHFFFAOYSA-N
一般描述
吡哆胺是维生素B6的一种衍生物。吡哆胺是一种水溶性维生素。维生素B6衍生物包含一个核心吡啶环。吡哆胺在吡啶的′4′位上含有一个氨甲基。
应用
5-磷酸吡哆胺适合于：
- 胞苷二磷酸-4-酮基-3,6-二脱氧葡萄糖的酶催化合成
- 作为5-磷酸吡哆胺磷酸酶活性测定的底物
- 作为表征5-吡i磷酸吡哆醇氧化酶的底物
- 用于NaBH4还原的糖原磷酸化酶b性质的吸收和荧光研究，以探测PMP残基的微环境
- 作为表征各种物种和组织中磷酸吡哆胺转氨酶的底物
生化/生理作用
以 (S)-α-甲基苄胺 (MBA) 为胺供体采用丙酮酸转氨酶生物催化剂可以将5′-磷酸吡哆醛转化为5′-磷酸吡哆胺。以黄素单核苷酸（FMN）为直接电子受体，氧为最终电子受体，通过大肠杆菌5′-磷酸吡哆醇（吡哆胺）氧化酶可以将5′-磷酸吡哆醇和5′-磷酸吡哆胺氧化成5′-磷酸吡哆醛（PLP）。
已通过吸收和荧光光谱研究评价了处于单重激发态的5′-磷酸吡哆胺的 p K （5-磷酸吡哆胺， PAMP ）。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
On the microenvironment of the pyridoxamine 5-phosphate residue in NaBH 4 -reduced glycogen phosphorylase b. Absorption and fluorescence studies.
M Cortijo et al.
European journal of biochemistry, 29(1), 134-142 (1972-08-18)
E S Yang et al.
Archives of biochemistry and biophysics, 377(1), 109-114 (2000-04-25)
Escherichia coli pyridoxine (pyridoxamine) 5'-phosphate oxidase (PNPOx) catalyzes the oxidation of pyridoxine 5'-phosphate and pyridoxamine 5'-phosphate to pyridoxal 5'-phosphate (PLP) using flavin mononucleotide (FMN) as the immediate electron acceptor and oxygen as the ultimate electron acceptor. This reaction serves as
L Lumeng et al.
The Journal of biological chemistry, 250(20), 8126-8131 (1975-10-25)
The tissue content of pyridoxal 5'-phosphate is controlled principally by the protein binding of this coenzyme and its hydrolysis by a cellular phosphatase. The present study identifies this enzyme and its intracellular location in rat liver. Pyridoxal-P is not hydrolyzed
J D Choi et al.
The Journal of biological chemistry, 258(2), 840-845 (1983-01-25)
The kinetic properties of pyridoxamine (pyridoxine)-5'-phosphate oxidase have been studied using the physiological substrates pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP) at 25 degrees C and pH 8.0. Under steady-state conditions with different concentrations of PNP and O2, a series
Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana.
Sang Y, Barbosa JM, Wu H, Locy RD, Singh NK.
Febs Letters, 2007, 344-348 (2007)
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