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Merck
CN

80760

Sigma-Aldrich

N-Myristoyl-D-sphingosine

≥98.0% (TLC)

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别名:
Cer(d18:1/14:0), (2S,3R,4E)-2-(Myristoylamino)-4-octadecene-1,3-diol, N-Myristoyl-D-erythro-sphingosine, N-Tetradecanoyl-D-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]tetradecanamide, C14 Ceramide (d18:1/14:0), C14-Ceramide
经验公式(希尔记法):
C32H63NO3
CAS号:
分子量:
509.85
Beilstein:
1717212
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.85

检测方案

≥98.0% (TLC)

形式

powder or solid

组成

carbon content, 75.37%
hydrogen content, 12.46%
nitrogen content, 2.75%

脂质类型

sphingolipids

运输

wet ice

储存温度

−20°C

SMILES字符串

OC[C@]([H])(NC(CCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C32H63NO3/c1-3-5-7-9-11-13-15-16-18-19-21-23-25-27-31(35)30(29-34)33-32(36)28-26-24-22-20-17-14-12-10-8-6-4-2/h25,27,30-31,34-35H,3-24,26,28-29H2,1-2H3,(H,33,36)/b27-25+/t30-,31+/m0/s1

InChI key

ZKRPGPZHULJLKJ-JHRQRACZSA-N

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Wei-Hung Jung et al.
EMBO reports, 18(7), 1150-1165 (2017-05-17)
Dihydroceramide desaturases are evolutionarily conserved enzymes that convert dihydroceramide (dhCer) to ceramide (Cer). While elevated Cer levels cause neurodegenerative diseases, the neuronal activity of its direct precursor, dhCer, remains unclear. We show that knockout of the fly dhCer desaturase gene
Wendi Teng et al.
Nutrients, 11(5) (2019-05-30)
Sulforaphane (SFA), a naturally active isothiocyanate compound from cruciferous vegetables used in clinical trials for cancer treatment, was found to possess potency to alleviate insulin resistance. But its underlying molecular mechanisms are still incompletely understood. In this study, we assessed
Baharan Fekry et al.
Nature communications, 9(1), 4149-4149 (2018-10-10)
Ceramides are important participants of signal transduction, regulating fundamental cellular processes. Here we report the mechanism for activation of p53 tumor suppressor by C16-ceramide. C16-ceramide tightly binds within the p53 DNA-binding domain (Kd ~ 60 nM), in close vicinity to the Box V

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