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Merck
CN

79710

Sigma-Aldrich

O-磷酸-DL-丝氨酸

≥98.0% (NT), suitable for cell culture

别名:

DL-2-氨基-3-羟基丙酸3-磷酸, DL-SOP, DL-丝氨酸单磷酸

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About This Item

经验公式(希尔记法):
C3H8NO6P
CAS号:
分子量:
185.07
Beilstein:
1726828
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

产品名称

O-磷酸-DL-丝氨酸, ≥98.0% (NT)

质量水平

方案

≥98.0% (NT)

表单

powder or crystals

技术

cell culture | mammalian: suitable

杂质

≤0.5% free serine (TLC)
≤1% water

颜色

white to faint beige

SMILES字符串

NC(COP(O)(O)=O)C(O)=O

InChI

1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)

InChI key

BZQFBWGGLXLEPQ-UHFFFAOYSA-N

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生化/生理作用

O-磷酸-DL-丝氨酸(pSer)用于研究非酶性氨基磷脂糖基化。
O-磷酸丝氨酸可用于通过O-磷酰基-tRNA:硒代半胱氨酰-tRNA合酶(SepSecS)催化的O-磷酸丝氨酸(Sep)的tRNA依赖性转化进行半胱氨酸和硒代半胱氨酸(Sec)的生物合成的替代途径中。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yoko Chiba et al.
The Journal of biological chemistry, 288(16), 11448-11458 (2013-03-13)
Novel-type serine-synthesizing enzymes, termed metal-independent phosphoserine phosphatases (iPSPs), were recently identified and characterized from Hydrogenobacter thermophilus, a chemolithoautotrophic bacterium belonging to the order Aquificales. iPSPs are cofactor-dependent phosphoglycerate mutase (dPGM)-like phosphatases that have significant amino acid sequence similarity to dPGMs
Po-Hsiang Wang et al.
The ISME journal, 13(4), 1042-1055 (2019-01-05)
Microbes in ecosystems often develop coordinated metabolic interactions. Therefore, understanding metabolic interdependencies between microbes is critical to deciphering ecosystem function. In this study, we sought to deconstruct metabolic interdependencies in organohalide-respiring consortium ACT-3 containing Dehalobacter restrictus using a combination of
Daniel Agren et al.
The Journal of biological chemistry, 283(46), 31567-31574 (2008-09-19)
The biosynthesis of cysteine is a crucial metabolic pathway supplying a building block for de novo protein synthesis but also a reduced thiol as a component of the oxidative defense mechanisms that appear particularly vital in the dormant state of
Seong-Jun Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(17), 6413-6418 (2014-04-16)
Mitochondrial dynamics is crucial for the regulation of cell homeostasis. Our recent findings suggest that hepatitis C virus (HCV) promotes Parkin-mediated elimination of damaged mitochondria (mitophagy). Here we show that HCV perturbs mitochondrial dynamics by promoting mitochondrial fission followed by
Anselm Sauerwald et al.
Science (New York, N.Y.), 307(5717), 1969-1972 (2005-03-26)
Several methanogenic archaea lack cysteinyl-transfer RNA (tRNA) synthetase (CysRS), the essential enzyme that provides Cys-tRNA(Cys) for translation in most organisms. Partial purification of the corresponding activity from Methanocaldococcus jannaschii indicated that tRNA(Cys) becomes acylated with O-phosphoserine (Sep) but not with

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