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Merck
CN

77631

Sigma-Aldrich

(R)-甲羟戊酸-5-焦磷酸 四锂盐

≥95% (TLC)

别名:

(R)-甲羟戊酸-5-二磷酸 四锂盐, R-MVAPP

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About This Item

经验公式(希尔记法):
C6H10Li4O10P2
分子量:
331.85
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.25

质量水平

方案

≥95% (TLC)

表单

powder

旋光性

[α]/D -2.9±0.5°, c = 1 in hydrochloric acid (0.02 M)

储存温度

−20°C

SMILES字符串

[Li+].[Li+].[Li+].[Li+].C[C@@](O)(CCOP([O-])(=O)OP([O-])([O-])=O)CC([O-])=O

InChI

1S/C6H14O10P2.4Li/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12);;;;/q;4*+1/p-4/t6-;;;;/m1..../s1

InChI key

GFIXUUFXTAPBAD-CZNRRTBNSA-J

相关类别

生化/生理作用

甲羟戊酸途径的代谢产物,在甾醇、多萜醇、血红素和泛醌的生物合成中起关键作用。在疾病肿瘤、自身免疫性疾病、动脉粥样硬化和阿尔茨海默病,以及遗传缺陷的甲羟戊酸激酶等研究领域受到关注。

包装

无底玻璃瓶。内含物装在锥底内插管中。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D McCaskill et al.
Analytical biochemistry, 215(1), 142-149 (1993-11-15)
Procedures for the isolation and analysis of all 11 intermediates of the mevalonic acid pathway from acetyl-CoA through geranylgeranyl pyrophosphate were developed. Both acid-labile and base-labile metabolites are simultaneously extracted with good recoveries into 7 M urea at neutral pH
Jonathan Lombard et al.
Molecular biology and evolution, 28(1), 87-99 (2010-07-24)
Isoprenoids are a very diverse family of organic compounds widespread in the three domains of life. Although they are produced from the condensation of the same precursors in all organisms (isopentenyl pyrophosphate and dimethylallyl diphosphate), the evolutionary origin of their
Rik van der Kant et al.
Cell stem cell, 24(3), 363-375 (2019-01-29)
Genetic, epidemiologic, and biochemical evidence suggests that predisposition to Alzheimer's disease (AD) may arise from altered cholesterol metabolism, although the molecular pathways that may link cholesterol to AD phenotypes are only partially understood. Here, we perform a phenotypic screen for

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