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Merck
CN

75440

Sigma-Aldrich

L-鸟氨酸 二盐酸盐

≥99.0% (AT)

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别名:
(S)-2,5-二氨基戊酸 二盐酸盐
经验公式(希尔记法):
C5H12N2O2 · 2HCl
CAS号:
分子量:
205.08
Beilstein:
4538819
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

质量水平

100
200

检测方案

≥99.0% (AT)

形式

crystals

旋光性

[α]20/D +17±1°, c = 5% in H2O

技术

ligand binding assay: suitable

灼烧残渣

≤0.1% (as SO4)

颜色

colorless

mp

197-199 °C (dec.)

痕量阴离子

sulfate (SO42-): ≤100 mg/kg

痕量阳离子

As: ≤0.1 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
NH4+: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES字符串

Cl.Cl.NCCC[C@H](N)C(O)=O

InChI

1S/C5H12N2O2.2ClH/c6-3-1-2-4(7)5(8)9;;/h4H,1-3,6-7H2,(H,8,9);2*1H/t4-;;/m0../s1

InChI key

HGBAVEGDXFHRQP-FHNDMYTFSA-N

生化/生理作用

L-Ornithine is a non-proteinogenic recycled component of the Urea Cycle leading to the production of arginine. L-ornithine is the starting compound for polyamine biosynthesis via ornithine decarboxylase.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Francois Blachier et al.
Frontiers in bioscience (Landmark edition), 16, 1331-1343 (2011-01-05)
Colon epithelium is renewed within few days through asymmetric mitosis of pluripotent cells followed by differentiation and exfoliation. Absorptive colonocytes do not transport amino acids from lumen to bloodstream but import amino acids from plasma. Among amino acids, colonocytes can
V Walker
Diabetes, obesity & metabolism, 11(9), 823-835 (2009-06-18)
The urea cycle is the final pathway for removal of surplus nitrogen from the body, and the major route in humans for detoxification of ammonia. The full complement of enzymes is expressed only in liver. Inherited deficiencies of urea cycle
Markus Munder
British journal of pharmacology, 158(3), 638-651 (2009-09-22)
The enzyme arginase metabolizes L-arginine to L-ornithine and urea. Besides its fundamental role in the hepatic urea cycle, arginase is also expressed the immune system of mice and man. While significant interspecies differences exist regarding expression, subcellular localization and regulation
Jens Schneider et al.
Applied microbiology and biotechnology, 91(1), 17-30 (2011-05-10)
In Bacteria, the pathways of polyamine biosynthesis start with the amino acids L-lysine, L-ornithine, L-arginine, or L-aspartic acid. Some of these polyamines are of special interest due to their use in the production of engineering plastics (e.g., polyamides) or as
Kazuyo Tujioka et al.
Journal of nutritional science and vitaminology, 58(5), 346-353 (2013-01-19)
The purpose of this study was to determine whether the regulation of brain protein synthesis is mediated through changes in the plasma concentration of growth hormone (GH) when dietary ornithine treatment is manipulated in the hypophysectomized or sham-operated aged rats.

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