74680
八甘醇单十二烷基醚
BioXtra, ≥98.0% (GC)
别名:
C12E8, 八甘醇十二烷基醚, 八甘醇单十二醚, 聚氧乙烯(8)月桂基醚
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关于此项目
线性分子式:
CH3(CH2)11(OCH2CH2)8OH
化学文摘社编号:
分子量:
538.75
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1893466
InChI
1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3
SMILES string
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI key
YYELLDKEOUKVIQ-UHFFFAOYSA-N
description
non-ionic
product line
BioXtra
assay
≥98.0% (GC)
form
solid
mol wt
538.75 g/mol
CMC
0.11
cation traces
Ca: ≤50 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cr: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, K: ≤50 mg/kg, Mg: ≤50 mg/kg, Mn: ≤50 mg/kg, Na: ≤50 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg
Quality Level
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General description
Octaethylene glycol monododecyl ether is a nonionic detergent.
Application
作为去污剂，用于研究天然样状态的膜蛋白，如 ATP酶。 用于中性pH下脂氧合酶的混合胶束检测以及用于流感病毒包膜的功能性重建。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
G C Troiano et al.
Biophysical journal, 75(2), 880-888 (1998-07-24)
The effects of a nonionic surfactant, octaethyleneglycol mono n-dodecyl ether (C12E8), on the electroporation of planar bilayer lipid membranes made of the synthetic lipid 1-pamitoyl 2-oleoyl phosphatidylcholine (POPC), was studied. High-amplitude ( approximately 100-450 mV) rectangular voltage pulses were used
[Relationship between activity and tetraprotomeric structure of ion-transporting ATPases].
Kazuhiro Abe et al.
Seikagaku. The Journal of Japanese Biochemical Society, 79(6), 527-534 (2007-08-01)
Cédric Montigny et al.
Biochemical and biophysical research communications, 391(1), 1067-1069 (2009-12-17)
Many membrane proteins become labile when they are solubilized by detergent. Here we show that the presence of high concentrations of glycyl betaine stabilizes one of these proteins, the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1a), solubilized with nonionic detergents like n-dodecyl beta-d-maltopyranoside
B Mavcic et al.
Bioelectrochemistry (Amsterdam, Netherlands), 63(1-2), 183-187 (2004-04-28)
Giant unilamellar phospholipid vesicles were prepared by the method of electroformation from 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine (POPC). We studied the influence of different concentrations of the surfactant octaethyleneglycol dodecylether (C(12)E(8)) on the spontaneous shape transformations of POPC vesicles at room temperature. In accordance
M Bobrowska-Hägerstrand et al.
Biophysical journal, 77(6), 3356-3362 (1999-12-10)
Endovesicles induced in human erythrocytes by octaethyleneglycol dodecylether (C12E8) were studied by confocal laser scanning microscopy, using fluorescein isothiocyanate dextran as a nonspecific fluid marker. The endovesicles appeared to consist mainly of a ring-formed toroidal part joined with a central
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