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文件

64319

Sigma-Aldrich

L-甲硫氨酸

≥99.5% (NT), BioUltra

别名:

L-2-氨基-4-（甲硫基）丁酸, （S）-2-氨基-4-（甲巯基）丁酸

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About This Item

线性分子式:
CH3SCH2CH2CH(NH2)CO2H
CAS号:
63-68-3
分子量:
149.21
Beilstein:
1722294
EC 号:
200-562-9
MDL编号:
MFCD00063097
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
57651979
NACRES:
NA.26

product name

L-甲硫氨酸, BioUltra, ≥99.5% (NT)

生物来源

synthetic

质量水平

200

产品线

BioUltra

检测方案

≥99.5% (NT)

形式

powder or crystals

旋光性

[α]20/D +23.7±0.5°, c = 5% in 5 M HCl

杂质

insoluble matter, passes filter test
≤0.5% foreign amino acids

灼烧残渣

≤0.1%

缺失

≤0.1% loss on drying, 20 °C (HV)

颜色

white

mp

284 °C (dec.) (lit.)

溶解性

1 M HCl: 0.5 M at 20 °C, clear, colorless

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

痕量阳离子

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤100 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.5 M in 1 M HCl

紫外吸收

λ: 260 nm Amax: 0.40
λ: 280 nm Amax: 0.05

SMILES字符串

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

基因信息

rat ... Ggt1(116568)

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相关类别

应用

<ul>
<li><strong>ROS-Responsive and Self-Tumor Curing Methionine Polymer Library Based Nanoparticles with Self-Accelerated Drug Release and Hydrophobicity/Hydrophilicity Switching Capability for Enhanced Cancer Therapy</strong>: This publication details the development of L-Methionine based nanoparticles, showcasing its pivotal role in advancing drug delivery systems for cancer treatment. The study highlights the potential of these systems in enhancing therapeutic efficacy through controlled drug release (Liu et al., 2024).</li>
<li><strong>N-acetyl-l-methionine dietary supplementation improves meat quality by oxidative stability of finishing Angus heifers</strong>: This study explores the benefits of L-Methionine supplementation in animal diets, emphasizing its impact on improving meat quality and oxidative stability, which is crucial for the meat production industry and nutritional science (Liu et al., 2024).</li>
</ul>

其他说明

合成用于傅立叶变换红外法L-戊二酸-513C酸质子化研究的标签；血清蛋白等速电泳间隔物；某些恶性人类细胞系培养基必需品；多种微生物的生长所需物质

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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W Kreis et al.
Cancer research, 40(3), 634-641 (1980-03-01)
Human embryonic lung fibroblasts (F-136-35-56) capable of growing in medium containing DL-homocysteine instead of L-methionine and human acute lymphoblastic leukemia cells (CCRF-HSB-2) with absolute methionine requirement exhibited dose-dependent growth inhibition when semipurified L-methionine-degrading enzyme (L-methioninase, EC 4.4.1.11) was added to
CRC Handbook of Microbiology, 4, 1-1 (1974)
T. Hine et al.
Electrophoresis ?83, 541-541 (1984)
W Kreis
Cancer treatment reports, 63(6), 1069-1072 (1979-06-01)
Published reports indicate that normal rodent cells can grow in medium containing either L-methionine or L-homocysteine, whereas malignant rodent cells have an absolute requirement for L-methionine. Our studies with two normal human cell lines (fetal lung fibroblasts and bladder epithelial
Bacteriorhodopsin: fourier transform infrared methods for studies of protonation of carboxyl groups.
G Dollinger et al.
Methods in enzymology, 127, 649-662 (1986-01-01)
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Chromatograms

application for HPLC

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