跳转至内容
Merck
CN

57510

Sigma-Aldrich

肌苷-5′-单磷酸 二钠盐 水合物

≥99.0% (HPLC)

登录查看公司和协议定价

别名:
5 & # 8242;-肌苷酸 二钠盐 水合物, 5′-IMP-Na2, I-5′-P, IMP, 肌苷酸
经验公式(希尔记法):
C10H11N4O8PNa2 · xH2O
分子量:
392.17 (anhydrous basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

质量水平

检测方案

≥99.0% (HPLC)

形式

powder or crystals

旋光性

[α]20/D −32±2°, c = 1% in H2O

杂质

~25% water

SMILES字符串

[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H13N4O8P.2Na.H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

KQCIGEIXDXQSGM-MSQVLRTGSA-L

正在寻找类似产品? 访问 产品对比指南

相关类别

应用

肌苷-5′-单磷酸盐 (5'-IMP) 可作为研究肌苷 5′ 的活性、特异性和动力学的底物-单磷酸脱氢酶 (IMPDH) 酶代码 EC 1.1.1.205,GMP 形成的限速酶和鸟嘌呤核苷酸池。

生化/生理作用

肌苷一磷酸或肌苷酸是次黄嘌呤的核糖核苷酸,是嘌呤合成过程中形成的第一个核苷酸。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Tomonori Nakanishi et al.
International immunopharmacology, 10(1), 91-97 (2009-10-21)
Inosine 5'-monophosphate dehydrogenase (IMPDH) inhibition is a critical target in solid organ transplantation, and the development of mycophenolate mofetil (MMF) represents a major advance in transplant medicine. In this study, the in vitro and in vivo pharmacological effects of BMS-566419
Inosine 5′-monophosphate dehydrogenase activity as a biomarker in the field of transplantation.
Glander P, Hambach P, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry (2011)
Chanporn Chaosap et al.
Food science of animal resources, 40(3), 338-349 (2020-05-20)
The effects of organic Zn-L-selenomethionine (Zn-L-SeMet) at 0.3 ppm on carcass composition, meat characteristics, fatty acid composition, glutathione peroxidase activity, and ribonucleotide content were compared against the commercial inorganic sodium selenite (Na-Se) and the combination of the two, in commercial
L Hedstrom et al.
Current medicinal chemistry, 18(13), 1909-1918 (2011-04-27)
Inosine 5'-monophosphate dehydrogenase (IMPDH) catalyzes the first committed step of guanosine 5'-monophosphate (GMP) biosynthesis, and thus regulates the guanine nucleotide pool, which in turn governs proliferation. Human IMPDHs are validated targets for immunosuppressive, antiviral and anticancer drugs, but as yet
Chi G Weindel et al.
eLife, 9 (2020-02-15)
The Parkinson's disease (PD)-associated gene leucine-rich repeat kinase 2 (LRRK2) has been studied extensively in the brain. However, several studies have established that mutations in LRRK2 confer susceptibility to mycobacterial infection, suggesting LRRK2 also controls immunity. We demonstrate that loss

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门