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Merck
CN

56395

Sigma-Aldrich

N-己酰基-L-高丝氨酸内酯

≥96% (HPLC)

别名:

N-[(3S)-四氢-2-氧代-3-呋喃基]己酰胺, N-己酰基-L-高丝氨酸内酯, C6-HSL, HHL

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About This Item

经验公式(希尔记法):
C10H17NO3
分子量:
199.25
Beilstein:
8143287
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.28

产品名称

N-己酰基-L-高丝氨酸内酯, ≥96% (HPLC)

质量水平

方案

≥96% (HPLC)

表单

powder or crystals

旋光性

[α]/D -32±3°, c = 0.2 in methanol

颜色

white to off-white

适用性

conforms to structure for Proton NMR spectrum

储存温度

−20°C

SMILES字符串

O=C1OCC[C@@H]1NC(CCCCC)=O

InChI

1S/C10H17NO3/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)/t8-/m0/s1

InChI key

ZJFKKPDLNLCPNP-QMMMGPOBSA-N

生化/生理作用

N-己酰基-L-高丝氨酸内酯是N-酰基-高丝氨酸内酯家族的成员。N-酰基高丝氨酸内酯(AHL)可调控革兰氏阴性细菌(如埃希氏菌沙门氏菌)的基因表达,参与群体感应、细菌的细胞间通讯;评论见。细菌的细胞间通讯成为新型抗毒力药物开发的靶标和预防生物膜形成的研究热点
群体感应信号发生

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Jeng Yeong Chow et al.
Biochemistry, 48(20), 4344-4353 (2009-04-21)
The PLL(PTE-like lactonase)-group of enzymes within the amidohydrolase superfamily hydrolyze N-acyl-homoserine lactones (AHLs) that are involved in bacterial quorum-sensing pathways. These enzymes possess the (beta/alpha)(8)-barrel fold and serve as attractive templates for in vitro evolution and engineering of quorum-quenching biological
Chi-I Chang et al.
Molecules (Basel, Switzerland), 24(11) (2019-06-13)
Three new dimeric abietane-type diterpenoids, abieta-6,8,11,13-tetraen-12-yl 12-hydroxyabieta-8,11,13-trien-7α-yl peroxide (1), abieta-6,8,11,13-tetraen-12-yl 12-hydroxyabieta-8,11,13-trien-7β-yl peroxide (2), and 12-hydroxyabieta-8,11,13-trien-7β-yl 7-oxoabieta-5,8,11,13-tetraen-12-yl peroxide (3), together with four known abietane-type diterpenoids (4-7) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were
Xue Yang et al.
Ultrasonics sonochemistry, 38, 19-28 (2017-06-22)
The effects of ultrasound pretreatment with different frequencies and working modes, including mono-frequency ultrasound (MFU), dual-frequency ultrasound (DFU) and tri-frequency ultrasound (TFU), on the degree of hydrolysis (DH) of rice protein (RP) and angiotensin-I-converting enzyme (ACE) inhibitory activity of RP
E S W Jones et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 107(10), 887-891 (2017-10-13)
Non-adherence to antihypertensives is a cause of 'pseudo-treatment-resistant' hypertension. To determine whether monitoring plasma amlodipine concentrations and inhibition of angiotensin-converting enzyme (ACE) can be adjunct adherence tools. Patients with hypertension who were prescribed enalapril and amlodipine were enrolled. Blood pressures
Fangmiao Yu et al.
Marine drugs, 16(11) (2018-10-31)
Marine-derived angiotensin-I converting enzyme (ACE) inhibitory peptides have shown potent ACE inhibitory activity with no side effects. In this study, we reported the discovery of a novel ACE-inhibitory peptide derived from trypsin hydrolysates of Cyclina sinensis (CSH). CSH was separated

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