56395
N-己酰基-L-高丝氨酸内酯
≥96% (HPLC)
别名:
N-[(3S)-四氢-2-氧代-3-呋喃基]己酰胺, N-己酰基-L-高丝氨酸内酯, C6-HSL, HHL
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关于此项目
经验公式（希尔记法）:
C10H17NO3
化学文摘社编号:
分子量:
199.25
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
Beilstein/REAXYS Number:
8143287
产品名称
N-己酰基-L-高丝氨酸内酯, ≥96% (HPLC)
SMILES string
O=C1OCC[C@@H]1NC(CCCCC)=O
InChI key
ZJFKKPDLNLCPNP-QMMMGPOBSA-N
InChI
1S/C10H17NO3/c1-2-3-4-5-9(12)11-8-6-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)/t8-/m0/s1
assay
≥96% (HPLC)
form
powder or crystals
optical activity
[α]/D -32±3°, c = 0.2 in methanol
color
white to off-white
suitability
conforms to structure for Proton NMR spectrum
storage temp.
−20°C
Quality Level
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Biochem/physiol Actions
N-己酰基-L-高丝氨酸内酯是N-酰基-高丝氨酸内酯家族的成员。N-酰基高丝氨酸内酯（AHL）可调控革兰氏阴性细菌（如埃希氏菌和沙门氏菌）的基因表达，参与群体感应、细菌的细胞间通讯；评论见。细菌的细胞间通讯成为新型抗毒力药物开发的靶标和预防生物膜形成的研究热点。
群体感应信号发生
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Chi-I Chang et al.
Molecules (Basel, Switzerland), 24(11) (2019-06-13)
Three new dimeric abietane-type diterpenoids, abieta-6,8,11,13-tetraen-12-yl 12-hydroxyabieta-8,11,13-trien-7α-yl peroxide (1), abieta-6,8,11,13-tetraen-12-yl 12-hydroxyabieta-8,11,13-trien-7β-yl peroxide (2), and 12-hydroxyabieta-8,11,13-trien-7β-yl 7-oxoabieta-5,8,11,13-tetraen-12-yl peroxide (3), together with four known abietane-type diterpenoids (4-7) were isolated from the methanol extract of the bark of Cryptomeria japonica. Their structures were
Jeng Yeong Chow et al.
Biochemistry, 48(20), 4344-4353 (2009-04-21)
The PLL(PTE-like lactonase)-group of enzymes within the amidohydrolase superfamily hydrolyze N-acyl-homoserine lactones (AHLs) that are involved in bacterial quorum-sensing pathways. These enzymes possess the (beta/alpha)(8)-barrel fold and serve as attractive templates for in vitro evolution and engineering of quorum-quenching biological
Xue Yang et al.
Ultrasonics sonochemistry, 38, 19-28 (2017-06-22)
The effects of ultrasound pretreatment with different frequencies and working modes, including mono-frequency ultrasound (MFU), dual-frequency ultrasound (DFU) and tri-frequency ultrasound (TFU), on the degree of hydrolysis (DH) of rice protein (RP) and angiotensin-I-converting enzyme (ACE) inhibitory activity of RP
E S W Jones et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 107(10), 887-891 (2017-10-13)
Non-adherence to antihypertensives is a cause of 'pseudo-treatment-resistant' hypertension. To determine whether monitoring plasma amlodipine concentrations and inhibition of angiotensin-converting enzyme (ACE) can be adjunct adherence tools. Patients with hypertension who were prescribed enalapril and amlodipine were enrolled. Blood pressures
Orrapun Selamassakul et al.
Journal of food science, 85(3), 707-717 (2020-02-12)
This study evaluated the biological properties of peptides from brown rice protein hydrolyzed by bromelain (eb-RPH) in relation to flavor characteristic. The fractionation into peptides < 1 kDa was observed to improve the DPPH, ABTS, and hydroxyl radical-scavenging activities (0.19, 2.28, and
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