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Merck
CN

53271

米托红

suitable for fluorescence, ≥70% (HPLC)

别名:

3,6-双（二乙氨基）-9- [2-（4-甲基香豆素-7-基氧羰基）苯基] 氯化黄药, 罗丹明 B 4-甲基伞形酮酯氯化物

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关于此项目

经验公式（希尔记法）:
C38H37ClN2O5
化学文摘社编号:
1021902-10-2
分子量:
637.16
NACRES:
NA.32
PubChem Substance ID:
329757927
UNSPSC Code:
41116100
MDL number:
MFCD05664720

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产品名称

米托红, suitable for fluorescence, ≥70% (HPLC)

InChI

1S/C38H37N2O5.ClH/c1-6-39(7-2)25-14-17-31-33(21-25)44-34-22-26(40(8-3)9-4)15-18-32(34)37(31)29-12-10-11-13-30(29)38(42)43-27-16-19-28-24(5)20-36(41)45-35(28)23-27;/h10-23H,6-9H2,1-5H3;1H/q+1;/p-1

SMILES string

[Cl-].CCN(CC)c1ccc2c(-c3ccccc3C(=O)Oc4ccc5C(C)=CC(=O)Oc5c4)c6ccc(cc6[o+]c2c1)N(CC)CC

InChI key

XCVSDCPWJRHMSZ-UHFFFAOYSA-M

assay

≥70% (HPLC)

form

solid

fluorescence

λex 569 nm; λem 594 nm in DMSO

suitability

suitable for fluorescence

storage temp.

2-8°C

Quality Level

100

Application

MitoRed (Mito Red) 是一种活体染料和线粒体染色剂，用于指示各种生理和物理条件下线粒体的状态。

General description

Mito Red 是一种细胞膜渗透性罗丹明基染料。它定位线粒体，并发出红色荧光。米托红与线粒体的相互作用依赖于线粒体的膜电位。线粒体可用 20-200 nM 的 Mito Red 染色。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCK5185
BCCG7265
BCCF2492
BCCB8006
BCBZ2229

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Wei-Lien Yen et al.
The Journal of cell biology, 188(1), 101-114 (2010-01-13)
Macroautophagy is a catabolic pathway used for the turnover of long-lived proteins and organelles in eukaryotic cells. The morphological hallmark of this process is the formation of double-membrane autophagosomes that sequester cytoplasm. Autophagosome formation is the most complex part of
Mamoru Kobayashi et al.
Human cell, 21(1), 7-11 (2008-01-15)
We investigated the mitochondrial behavior, localization and heteroplasmy in reconstituted oocytes derived from germinal vesicle (GV) transfers. The karyoplast containing the GV nucleus and the ooplast (enucleated oocyte) were prepared from GV oocytes derived from B6D2F1 mice. Mitochondria in the
Taeko Horinouchi et al.
Bioorganic & medicinal chemistry letters, 21(7), 2000-2002 (2011-03-08)
We report a novel green-fluorescent NO donor, NBDNO, bearing a 2,6-dimethylnitrobenzene moiety for photocontrollable NO release and a triphenylphosphonium moiety for targeting to mitochondria. Photorelease of NO from NBDNO was confirmed by means of ESR analysis in aqueous solution. Intracellular
Yumiko Nagano et al.
Digestive diseases and sciences, 50 Suppl 1, S76-S83 (2005-09-27)
Nonsteroidal antiinflammatory drugs (NSAIDs) cause complications such as gastrointestinal injury. NSAIDs were recently reported to cause mitochondrial injury: to dissipate the mitochondrial transmembrane potential (MTP), and to induce mitochondrial permeability transition pore (PTP), which liberates cytochrome c. This enzyme generates
Fanny Joanny et al.
Antimicrobial agents and chemotherapy, 56(11), 5982-5985 (2012-08-02)
Many successful antimicrobial drugs originate from synthetic dyes. This paper reports the in vitro activity of 14 fluorescent dyes against Plasmodium falciparum. Five of these dyes (Hoechst 33342, MitoRed, DiOC(6), SYTO 9, and rhodamine B) show activity at a low
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感应染料

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。

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