跳转至内容
Merck
CN

51120

Sigma-Aldrich

5′-三磷酸鸟苷 钠盐 水合物

≥90% (HPLC)

别名:

GTP-Na⁺ 水合物, 5′-GTP-Na2

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C10H16N5O14P3 · xNa+ · yH2O
CAS号:
分子量:
523.18 (anhydrous free acid basis)
Beilstein:
4113439
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

质量水平

检测方案

≥90% (HPLC)

形式

powder

旋光性

[α]20/D −24±2°, c = 1% in 0.5 M Na2HPO4

杂质

≤3 mol/mol water (NMR)

运输

wet ice

储存温度

−20°C

SMILES字符串

O.O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H16N5O14P3.2Na.2H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;2*1H2/q;2*+1;;/p-2/t3-,5-,6-,9-;;;;/m1..../s1

InChI key

HPLNHYUZFVUXFJ-ZVQJTLEUSA-L

正在寻找类似产品? 访问 产品对比指南

一般描述

5′-三磷酸鸟苷(GTP)是一种嘌呤三核苷酸磷酸。GTP是各种G-蛋白偶联受体(GPCR)GTP酶及细胞信号转导和GTP/GDP循环相关鸟嘌呤核苷酸交换因子(GEF)的底物。如需进行RNA聚合酶转录、DNA/RNA生物合成,请访问G3776产品。

应用

鸟苷 5′-三磷酸钠盐水合物已用于:
  • 作为星形胶质细胞膜片钳内液的组成部分,监测小鼠杏仁核切片星形胶质细胞的钙活性。
  • 利用电压钳技术记录细胞系中通道电流的溶液。
  • 制备内部记录注射溶液,用于将基因传递到机械感觉毛细胞。
  • 在通过体积排除色谱法(SEC)分析齐聚反应过程中,促进G界面介导的人septin蛋白同源二聚体的形成。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Gyu-Sang Hong et al.
Neuron, 94(2), 271-273 (2017-04-21)
Mechanosensation is essential for various physiological processes, and it is mediated by mechanotransduction channels. Recently, we reported that TMEM150C/Tentonin 3 (TTN3) confers mechanically activated currents with slow inactivation kinetics in several cell types, including dorsal root ganglion neurons (Hong et al.
Lukas Jakob Neukomm et al.
Development (Cambridge, England), 138(10), 2003-2014 (2011-04-15)
Multicellular organisms use programmed cell death to eliminate unwanted or potentially harmful cells. Improper cell corpse removal can lead to autoimmune diseases. The development of interventional therapies that increase engulfment activity could represent an attractive approach to treat such diseases.
Hiroaki Kajiho et al.
The Journal of biological chemistry, 286(27), 24364-24373 (2011-05-19)
The small GTPase Rab5, which cycles between GDP-bound inactive and GTP-bound active forms, plays essential roles in membrane budding and trafficking in the early endocytic pathway. Rab5 is activated by various vacuolar protein sorting 9 (VPS9) domain-containing guanine nucleotide exchange
Fu-Jung Chang et al.
The Journal of biological chemistry, 280(12), 11513-11519 (2005-01-15)
The mechanism of desensitization of the nitric oxide (NO) receptor (alpha1.beta1 isoform of soluble guanylyl cyclase, sGC) is not known. Models of the structure of alpha1.beta1, based on the x-ray crystal structure of adenylyl cyclase (AC) suggest the existence of
M Uriarte et al.
The Biochemical journal, 293 ( Pt 1), 93-100 (1993-07-01)
A glycoprotein fraction was isolated from rat liver membranes by affinity chromatography on immobilized wheat-germ lectin. Incubation of this fraction with MgATP or MgGTP resulted in a sequential phosphorylation and dephosphorylation of a complex of three polypeptides (118, 128 and

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门