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Merck
CN

49225

Sigma-Aldrich

α-D-Glucose 1,6-bisphosphate potassium salt hydrate

≥99.0% (TLC)

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别名:
α-D-Glucose 1,6-diphosphate potassium salt hydrate
经验公式(希尔记法):
C6H10K4O12P2 · xH2O
CAS号:
分子量:
492.48 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

质量水平

检测方案

≥99.0% (TLC)

形式

solid

杂质

≤15% water

颜色

white

溶解性

H2O: 50 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

[K+].[K+].[K+].[K+].O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@H](OP([O-])([O-])=O)[C@@H]1O

InChI

1S/C6H14O12P2.4K/c7-3-2(1-16-19(10,11)12)17-6(5(9)4(3)8)18-20(13,14)15;;;;/h2-9H,1H2,(H2,10,11,12)(H2,13,14,15);;;;/q;4*+1/p-4/t2-,3-,4+,5-,6-;;;;/m1..../s1

InChI key

OVRXVCAVDXBPQT-QMKHLHGBSA-J

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应用

α-D-Glucose 1,6-bisphosphate is used in the identification, differentiation and characterization of α-phosphoglucomutase(s), β-phosphoglucomutase(s) and α- and β-hexoglucomutase(s).

生化/生理作用

Metabolite formed via the activity of Glucose-1,6-biphosphate synthase. Glucose-1,6-biphosphate (G-1,6-BP) acts as an inhibitor of hexokinase function and an activator of phosphofructokinase-1 and pyruvate kinase. G-1,6-BP also acts as a coenzyme for phosphoglucomutate and a cofactor for phosphopentomutase.

其他说明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

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Jessica P Lao et al.
G3 (Bethesda, Md.), 9(2), 413-423 (2018-12-12)
Phosphomannomutase 2 Deficiency (PMM2-CDG) is the most common monogenic congenital disorder of glycosylation (CDG) affecting at least 800 patients globally. PMM2 orthologs are present in model organisms, including the budding yeast Saccharomyces cerevisiae gene SEC53 Here we describe conserved genotype-phenotype

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