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42364

Sigma-Aldrich

1，1′-二十八烷基-3，3，3′，3′-四甲基吲哚菁高氯酸盐

suitable for fluorescence, BioReagent, ≥98.0% (TLC)

别名:

DiI

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About This Item

经验公式（希尔记法）:
C59H97ClN2O4
CAS号:
41085-99-8
分子量:
933.87
Beilstein:
8251870
MDL编号:
MFCD00142354
UNSPSC代码:
12171500
PubChem化学物质编号:
57650110
NACRES:
NA.32

产品线

BioReagent

质量水平

100

检测方案

≥98.0% (TLC)

mp

68 °C (dec.) (lit.)

溶解性

DMF: soluble
DMSO: soluble
methanol: soluble

荧光

λex 550 nm; λem 567 nm in phosphate buffer/SDS pH 7.0

适用性

suitable for fluorescence

SMILES字符串

[O-]Cl(=O)(=O)=O.CCCCCCCCCCCCCCCCCCN1c2ccccc2C(C)(C)/C1=C\C=C\C3=[N+](CCCCCCCCCCCCCCCCCC)c4ccccc4C3(C)C

InChI

1S/C59H97N2.ClHO4/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-41-50-60-54-46-39-37-44-52(54)58(3,4)56(60)48-43-49-57-59(5,6)53-45-38-40-47-55(53)61(57)51-42-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2;2-1(3,4)5/h37-40,43-49H,7-36,41-42,50-51H2,1-6H3;(H,2,3,4,5)/q+1;/p-1

InChI key

JVXZRNYCRFIEGV-UHFFFAOYSA-M

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相关类别

一般描述

DiI 是染料 Aye，一种 CAS 号为 41085-99-8 的化学品。它是荧光亲脂性阳离子吲哚菁染料，通常制成高氯酸盐。主要用于科学染色目的，例如单分子成像、命运绘图和神经元追踪（因为 DiI 保留在脂质双层膜中）。

应用

1，1′-二十八烷基-3，3，3′，3′-四甲基吲哚菁高氯酸盐用于以下应用：
  • DIL 溶液的制备
  • 荧光膜染料
  • Di-I 染色

生化/生理作用

亲脂性羰花青染料主要用于膜电压的光学记录和膜流动性的研究。用于神经元的逆行染色；在体内和体外提供对活神经元的强烈、持久的染色。

其他说明

用于研究膜的亲脂荧光探针

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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R D Klausner et al.
Biochemistry, 19(26), 6199-6203 (1980-12-23)
We have examined the phase partition preferences of the even chain length (n = 10-22) diacyl-3'3'-indocarbo-cyanine iodides (Cn diI) incorporated in disaturated lecithin (PC) vesicles. Two parameters were used to determine this phase preference: (i) the direction of shift of
Calorimetric investigation of the phase partitioning of the fluorescent carbocyanine probes in phosphatidylcholine bilayers.
M F Ethier et al.
Biochemistry, 22(5), 1178-1182 (1983-03-01)
Ralph Michael et al.
Vision research, 48(4), 626-634 (2008-01-29)
We evaluated the gross morphology, location, and fiber cell architecture of equatorial cortical opacities in the aging human lens. Using dark-field stereomicroscopy, we photographed donor lenses in toto and as thick slices. In addition, we investigated the details of the
Guang-Di Chen et al.
Neural plasticity, 2014, 658741-658741 (2014-06-04)
Previous studies have shown that sodium salicylate (SS) activates not only central auditory structures, but also nonauditory regions associated with emotion and memory. To identify electrophysiological changes in the nonauditory regions, we recorded sound-evoked local field potentials and multiunit discharges
Muhammad Umar Jawad et al.
PloS one, 5(12), e14250-e14250 (2010-12-21)
In carcinomas stromal cells participate in cancer progression by producing proteases such as MMPs. The expression MMP1 is a prognostic factor in human chondrosarcoma, however the role in tumor progression is unknown. Laser capture microdissection and In Situ hybridization were
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