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Merck
CN

41525

N,N-Dimethyl-6-propionyl-2-naphthylamine

BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

别名:

2-(Dimethylamino)-6-propionylnaphthalene, 6-Propionyl-2-(dimethylamino)naphthalene, Prodan

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关于此项目

经验公式（希尔记法）:
C15H17NO
化学文摘社编号:
70504-01-7
分子量:
227.30
UNSPSC Code:
12352116
NACRES:
NA.32
PubChem Substance ID:
57650063
MDL number:
MFCD00056615
Beilstein/REAXYS Number:
2723587

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产品名称

N,N-Dimethyl-6-propionyl-2-naphthylamine, BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

InChI

1S/C15H17NO/c1-4-15(17)13-6-5-12-10-14(16(2)3)8-7-11(12)9-13/h5-10H,4H2,1-3H3

SMILES string

CCC(=O)c1ccc2cc(ccc2c1)N(C)C

InChI key

MPPQGYCZBNURDG-UHFFFAOYSA-N

product line

BioReagent

assay

≥98.0% (HPLC)

form

solid

mp

137 °C (lit.)

solubility

DMF: soluble
acetone: soluble
acetonitrile: soluble
methanol: soluble

fluorescence

λex 361 nm; λem 498 nm in methanol

suitability

suitable for fluorescence

Quality Level

100

相关类别

Application

N,N-Dimethyl-6-propionyl-2-naphthylamine (Prodan), a membrane surface probe, may be used as a fluorescence probe in non-cell based in vitro assay for the determination of drug-phospholipid complex formation and to study membrane surface properties.

Other Notes

Fluorescence of spectrin-bound Prodan

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCP1667
BCCL7745
BCCH9139
BCCH9138
BCCF1912

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Masaki Goto et al.
Langmuir : the ACS journal of surfaces and colloids, 26(16), 13377-13384 (2010-08-11)
The bilayer phase behavior of diheptadecanoylphosphatidylcholine (C17PC) with different vesicle sizes (large multilamellar vesicle (LMV) and giant multilamellar vesicle (GMV)) was investigated by fluorescence spectroscopy using a polarity-sensitive fluorescent probe Prodan under atmospheric and high pressures. The difference in phase
Justyna Barucha-Kraszewska et al.
Biochimica et biophysica acta, 1798(9), 1724-1734 (2010-06-01)
Fluorescence methods are widely used in studies of biological and model membranes. The dynamics of membrane fluorescent markers in their ground and excited electronic states and correlations with their molecular surrounding within the fully hydrated phospholipid bilayer are still not
Ramkrishna Adhikary et al.
The journal of physical chemistry. B, 113(35), 11999-12004 (2009-08-28)
The coexistence of different excited states with different properties of the same chromophores could have significant consequences for the accurate characterization of solvation dynamics in a heterogeneous environment, such as a protein. The purpose of this work is to study
Masaki Goto et al.
Colloids and surfaces. B, Biointerfaces, 84(1), 55-62 (2011-01-15)
The bilayer phase behavior of asymmetric phospholipids, palmitoylstearoylphosphatidylcholine (PSPC) and stearoylpalmitoylphosphatidylcholine (SPPC), with different vesicle sizes (large multilamellar vesicle (LMV) and giant multilamellar vesicle (GMV)) was investigated by fluorescence spectroscopy using a polarity-sensitive fluorescent probe Prodan under high pressure. The
E K Krasnowska et al.
Biochimica et biophysica acta, 1511(2), 330-340 (2001-04-05)
The fluorescent membrane probe 6-propionyl-2-dimethylaminonaphthalene (Prodan) displays a high sensitivity to the polarity and packing properties of lipid membrane. Contrary to 6-lauroyl-2-dimethylaminonaphthalene (Laurdan), Prodan can also monitor the properties of the membrane surface, i.e., the polar-head pretransition. In bilayers composed
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