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Merck
CN
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37920

Sigma-Aldrich

6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt

BioReagent, suitable for fluorescence, ≥97.0% (HPCE)

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别名:
DHPDS, Disodium 6,8-dihydroxy-1,3-pyrenedisulfonate
经验公式（希尔记法）:
C16H8Na2O8S2
CAS号:
61255-63-8
分子量:
438.34
Beilstein:
8962638
MDL编号:
MFCD00800283
UNSPSC代码:
12352106
PubChem化学物质编号:
57649723
NACRES:
NA.32

产品线

BioReagent

质量水平

100

检测方案

≥97.0% (HPCE)

形式

powder

pKa 

7.33
8.53

mp

≥250 °C (lit.)

溶解性

DMF: soluble
H2O: soluble
methanol: soluble

荧光

λex 405 nm; λem 456 nm in 0.1 M citrate pH 3.0
λex 458 nm; λem 498 nm in 0.1 M Tris pH 8.0

适用性

suitable for fluorescence

SMILES字符串

[Na+].[Na+].Oc1cc(O)c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H10O8S2.2Na/c17-11-5-12(18)8-2-4-10-14(26(22,23)24)6-13(25(19,20)21)9-3-1-7(11)15(8)16(9)10;;/h1-6,17-18H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2

InChI key

JISMNCQKTAIERN-UHFFFAOYSA-L

应用

6,8-Dihydroxy-1,3-pyrenedisulfonic acid (DHPDS) is a pH-sensitive dye that may be used to measure pH changes inside cells (pHi). DHPDS is used to create charge transfer complexes for studies on nanostructure assembly.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

其他说明

Highly water soluble pH indicator for the physiological range

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Chao Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 26(18), 14509-14511 (2010-08-21)
We have demonstrated a hierarchical self-assembly of the nanoribbons on the basis of the concept of a superamphiphile. A viologen-containing surfactant (RV) and a water-soluble electron donor, 6,8-dihydroxypyrene-1,3-disulfonic acid disodium (DHP), are mixed in water to form a charge transfer
K Hanaoka et al.
Nihon rinsho. Japanese journal of clinical medicine, 50(9), 2048-2053 (1992-09-01)
Since various cellular processes depend on changes in pH, the regulation of intracellular pH (pHi) is important both for the individual cell and for the organism. The mechanisms of the regulation of pHi can be investigated by monitoring pHi. In
Aron Hakonen et al.
Talanta, 80(5), 1964-1969 (2010-02-16)
This study presents a high-performance ratiometric pH optode based on the fluorophore 6,8-dihydroxypyrene-1,3-disulfonic acid (DHPDS). The two pH-sensitive terminal hydroxy groups of DHPDS facilitated dual excitation/dual emission (F(1): lambda(1,ex)=420 nm, lambda(1,em)=462 nm; F(2): lambda(2,ex)=470 nm, lambda(2,em)=498 nm) properties for ratiometric
O.S. Wolfbeis et al.
Fresenius Journal of Analytical Chemistry, 314, 119-119 (1983)
F X Felberbauer et al.
Pflugers Archiv : European journal of physiology, 419(2), 215-217 (1991-09-01)
The pH-sensitive fluorescent dye 1,3-dihydroxy-pyrene-6,8-disulfonic acid (DHPDS) was used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver. Monochromatic light from a fluorometer was focused on the liver with a fiber optic, emitted light

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