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Merck
CN

31149

脱氧核糖核酸,低分子量 来源于鲑鱼精子

别名:

鲑鱼精子dsDNA, DNA

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关于此项目

化学文摘社编号:
UNSPSC Code:
41106310
eCl@ss:
32160414
EC Number:
309-566-6
NACRES:
NA.52
MDL number:
Biological source:
fish
Form:
lyophilized powder
Solubility:
50 mM Tris pH 8.0: 10 mg/mL, clear, faintly brown-yellow
Storage temp.:
2-8°C
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biological source

fish

grade

Molecular Biology, puriss. p.a.

form

lyophilized powder

impurities

≤5% protein

solubility

50 mM Tris pH 8.0: 10 mg/mL, clear, faintly brown-yellow

absorbance ratio

A260/280 nm ~1.4

storage temp.

2-8°C

Application

从鲑鱼精子中提取的不同浓度的低分子量脱氧核糖核酸已用于:
  • 研究DNA与硅取代羟基磷灰石纳米晶体的结合。
  • 在简单的电化学DNA生物传感器中检测和评估UV-C辐射和活性氧造成的DNA损伤。
  • 作为合成生物点的前体。

Biochem/physiol Actions

在各种研究应用中,鲑鱼精子DNA常被用作阻断剂。 已知它可以通过减少非特异性结合和背景信号来提高多AP测定的特异性和敏感性。


存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

动植物源性产品
低风险生物材料

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历史批次信息供参考:

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Andrea Hájková et al.
Bioelectrochemistry (Amsterdam, Netherlands), 116, 1-9 (2017-03-18)
A simple electrochemical DNA biosensor based on a glassy carbon electrode (GCE) was prepared by adsorbing double-stranded DNA (dsDNA) onto the GCE surface and subsequently used for the detection of dsDNA damage induced by hydroxyl radicals. Investigation of the mutual
J J Gao et al.
Journal of immunology (Baltimore, Md. : 1950), 166(11), 6855-6860 (2001-05-22)
LPS is well recognized for its potent capacity to activate mouse macrophages to produce TNF-alpha, an important inflammatory mediator in bacterial infection-related diseases such as septic shock. We demonstrate here that while inducing only low levels of TNF-alpha alone, DNA
Eiji Sunami et al.
Clinical chemistry, 55(3), 559-567 (2009-01-10)
Prostate cancer (PCa) detection using serum-based prostate specific antigen (PSA) is limited by frequent false-positive and -negative results. Genetic aberrations such as allelic imbalance (AI) and epigenetic changes such as promoter hypermethylation have been detected in circulating DNA of cancer



全球贸易项目编号

货号GTIN
31149-10G-F04061826681626
31149-50G-F04061826681633