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Merck
CN

30906

蓖麻油,乙氧基化

别名:

PEG-35 蓖麻油, 聚氧乙烯蓖麻油

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化学文摘社编号:
UNSPSC Code:
12161900
NACRES:
NA.25
MDL number:
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SMILES string

ClCC(OC(=O)N)CCl

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

description

non-ionic

form

paste

impurities

alkalinity, complies, ≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only), ≤0.1% oleic acid, ≤0.1% palmitic acid, ≤0.2% sulfated ash (verfied on random samples only), ≤0.20% ricinoleic acid, ≤0.5% water, ≤1 ppm ethylene oxide (verfied on random samples only), ≤1.0% free fatty acids, ≤10 ppm dioxan (verfied on random samples only), ≤10 ppm heavy metals (verfied on random samples only), ≤620 ppm diethylene glycol (verfied on random samples only), ≤620 ppm ethylene glycol (verfied on random samples only)

ign. residue

≤0.2%

pH

5.0-7.0 (1 g/10 mL in H2O)

viscosity

600-750 mPa.s(25 °C)

acid value

≤2.0 mg KOH/g

hydroxyl value

65‑78 mg KOH/g

iodine value

25‑35 g/100g

saponification value

65‑70 mg KOH/g

cation traces

K: ≤15 ppm

Quality Level

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Application

乙氧基化蓖麻油可用于乳化和溶解油类和其它不溶于水的物质。 与乙氧基化蓖麻油相似,但含水量较低,且粘度不同。

Analysis Note

相对密度 D (25/25) 1.05-1.06

Legal Information

Cremophor is a registered trademark of BASF SE

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

494.6 °F - Not applicable

flash_point_c

257 °C - Not applicable


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Clinical cancer research : an official journal of the American Association for Cancer Research, 8(5), 1038-1044 (2002-05-15)
ABI-007 is a novel Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel. The absence of Cremophor EL may permit ABI-007 to be administered without the premedications used routinely for the prevention of hypersensitivity reactions. Furthermore, this novel formulation permits a higher paclitaxel
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International journal of pharmaceutics, 246(1-2), 75-83 (2002-09-25)
The optimized formulation of N-4472, N-[2-(3,5-di-tert-butyl-4-hydroxyphenethyl)-4,6-difluorophenyl]-N'-[4-(N-benzylpiperidyl)] urea, which was a poorly water-soluble drug, was developed by utilizing the complexation between N-4472 and L-ascorbic acid (VC). It was found that the formulation with Gelucire((R)) 44/14, HCO-60((R)) and sodium dodecyl sulfate provided
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Ophthalmology, 109(11), 2030-2035 (2002-11-05)
We developed low-concentration homogenized castor oil eye drops for the treatment of patients with noninflamed obstructive meibomian gland dysfunction (MGD), a major cause of lipid-deficiency dry eye, and assessed the safety, stability, and efficacy of the eye drops. Randomized, double-masked
Yun-Seok Rhee et al.
Archives of pharmacal research, 30(1), 114-123 (2007-03-03)
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Allergic contact dermatitis to polyethylene glycol-7 hydrogenated castor oil.
M Kalavala et al.
Contact dermatitis, 56(5), 287-288 (2007-04-20)

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