杂质
ethylene glycol, complies (meets the requirements of Macrogol Polyvinylalcohol Grafted Copolymer Ph Eur Ed. 7)
≤1 ppm ethylene oxide
≤10 ppm dioxan
≤100 ppm vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals
质量水平
灼烧残渣
≤2%
缺失
≤5% loss on drying
pH值（酸碱度）
5.0-8.0 (20% in H2O)
粘度
50-250 mPa.s, 20 %(23 °C, Brookfield RVT) (SP.2, 100RPM)
酯化值
10‑70 mg KOH/g
应用
Kollicoat IR在制药工业中用作粘合剂、粒料和颗粒物质。该研究等级产物只可用于 R&D和研发用途。
法律信息
Kollicoat is a registered trademark of BASF SE
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Susanne Muschert et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(1), 130-137 (2009-01-17)
The aim of this study was to better understand the underlying drug release mechanisms from aqueous ethylcellulose-coated pellets containing different types of drugs and starter cores. Theophylline, paracetamol, metoprolol succinate, diltiazem HCl and metoprolol tartrate were used as model drugs
Sandra Guns et al.
Pharmaceutical research, 28(3), 673-682 (2010-11-26)
To investigate the effect of the manufacturing method (spray-drying or hot-melt extrusion) on the kinetic miscibility of miconazole and the graft copolymer poly(ethyleneglycol-g-vinylalcohol). The effect of heat pre-treatment of solutions used for spray-drying and the use of spray-dried copolymer as
Kyung Jin Son et al.
ACS applied materials & interfaces, 3(2), 573-581 (2011-02-05)
In this study, we describe the use of organized mesoporous titanium oxide (TiO(2)) films as three-dimensional templates for protein microarrays with enhanced protein loading capacity and detection sensitivity. Multilayered mesoporous TiO(2) films with high porosity and good connectivity were synthesized
Pan Liu et al.
Journal of pharmaceutical sciences, 101(8), 2811-2820 (2012-05-23)
The objective of this study was to investigate the drug release mechanism and in vivo performance of Tanshinone IIA sustained-release pellets, coated with blends of polyvinyl acetate (PVAc) and poly(vinyl alcohol)-poly(ethylene glycol) (PVA-PEG) graft copolymer. A formulation screening study showed
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