30320
5-′三磷酸胞苷 二钠盐 水合物
≥90.0% (HPLC), solid
别名:
5-CTP-Na2, CTP
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关于此项目
经验公式（希尔记法）:
C9H14N3Na2O14P3 · xH2O
化学文摘社编号:
分子量:
527.12 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Beilstein/REAXYS Number:
3582735
Assay:
≥90.0% (HPLC)
Form:
solid
Solubility:
H2O: 50 mg/mL, clear, colorless
Storage temp.:
−20°C
产品名称
5-′三磷酸胞苷 二钠盐 水合物, ≥90.0% (HPLC)
InChI
1S/C9H16N3O14P3.2Na.H2O/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1
SMILES string
O.[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O
InChI key
IJMSOWKYYIROGP-LLWADOMFSA-L
assay
≥90.0% (HPLC)
form
solid
impurities
≤12% water
solubility
H2O: 50 mg/mL, clear, colorless
shipped in
wet ice
storage temp.
−20°C
Quality Level
Application
胞苷5′-三磷酸二钠盐水合物已用于：
- 银纳米团簇寡核苷酸合成的交互效应研究
- 作为荧光发射的阴离子源和竹红菌甲素A-锌（III）配合物和滴定曲线分析
- 铜（II）-2，6-双（2-苯并咪唑基）吡啶配合物的荧光发射实验
胞苷5γ-三磷酸（CTP）用于各种RNA聚合酶合成RNA。胞苷5γ-三磷酸（CTP）是CMP-neuNAc合成酶的底物，该酶产生用于唾液酸化反应的CMP-neuNAc。作为CTP：磷酸胆碱胞苷转移酶（CT）的底物，CTP通过CDP-胆碱的形成支持磷脂酰胆碱的形成。
Biochem/physiol Actions
胞苷5′-三磷酸（CTP）对于DNA的合成至关重要，并且是生命系统中许多生理过程的介体。对二醇磷酸化，胆固醇转运至关重要，并参与天冬氨酸转氨甲酰酶的变构调节。它也用于疾病相关脑的治疗。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
Ratiometric Detection of Adenosine-5?-triphosphate (ATP) and Cytidine-5?-triphosphate (CTP) with a Fluorescent Spider-Like Receptor in Water
Gupta AK, et al.
European Journal of Organic Chemistry, 2015(1), 122-129 (2015)
Selective fluorometric detection of pyrophosphate and stringent alarmone with copper (II)-2, 6-bis (2-benzimidazolyl) pyridine complex
Zhao XJ and Huang CZ
Biosensors And Bioelectronics, 30(1), 282-286 (2011)
Melissa A MacKinnon et al.
The Journal of biological chemistry, 284(11), 7376-7384 (2009-01-15)
Phosphatidylcholine is the major phospholipid in eukaryotic cells. There are two main pathways for the synthesis of phosphatidylcholine: the CDP-choline pathway present in all eukaryotes and the phosphatidylethanolamine methylation pathway present in mammalian hepatocytes and some single celled eukaryotes, including
Highly selective detection of bacterial alarmone ppGpp with an off-on fluorescent probe of copper-mediated silver nanoclusters
Zhang P, et al.
Biosensors And Bioelectronics, 49(1), 433-437 (2013)
J Vionnet et al.
Glycobiology, 9(5), 481-487 (1999-04-20)
CMP-beta-N-acetylneuraminic acid (CMP-neuNAc) is the substrate for the sialylation of glycoconjugates by sialyltransferases in microbes and higher eukaryotes. CMP-neuNAc synthetase catalyzes the formation of this substrate, CMP-neuNAc, from CTP and neuNAc. In this report we describe the purification of CMP-neuNAc
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