所有图片(1)
别名:
5-CTP-Na2, CTP
经验公式（希尔记法）:
C9H14N3Na2O14P3 · xH2O
CAS号:
分子量:
527.12 (anhydrous basis)
Beilstein:
3582735
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
推荐产品
质量水平
检测方案
≥90.0% (HPLC)
形式
solid
杂质
≤12% water
溶解性
H2O: 50 mg/mL, clear, colorless
运输
wet ice
储存温度
−20°C
SMILES字符串
O.[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O
InChI
1S/C9H16N3O14P3.2Na.H2O/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1
InChI key
IJMSOWKYYIROGP-LLWADOMFSA-L
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应用
胞苷5′-三磷酸二钠盐水合物已用于：
- 银纳米团簇寡核苷酸合成的交互效应研究
- 作为荧光发射的阴离子源和竹红菌甲素A-锌（III）配合物和滴定曲线分析
- 铜（II）-2，6-双（2-苯并咪唑基）吡啶配合物的荧光发射实验
胞苷5γ-三磷酸（CTP）用于各种RNA聚合酶合成RNA。胞苷5γ-三磷酸（CTP）是CMP-neuNAc合成酶的底物，该酶产生用于唾液酸化反应的CMP-neuNAc。作为CTP：磷酸胆碱胞苷转移酶（CT）的底物，CTP通过CDP-胆碱的形成支持磷脂酰胆碱的形成。
生化/生理作用
胞苷5′-三磷酸（CTP）对于DNA的合成至关重要，并且是生命系统中许多生理过程的介体。对二醇磷酸化，胆固醇转运至关重要，并参与天冬氨酸转氨甲酰酶的变构调节。它也用于疾病相关脑的治疗。
WGK
WGK 3
闪点(°F)
235.4 °F
闪点(°C)
113 °C
个人防护装备
Eyeshields, Gloves, type N95 (US)
Melissa A MacKinnon et al.
The Journal of biological chemistry, 284(11), 7376-7384 (2009-01-15)
Phosphatidylcholine is the major phospholipid in eukaryotic cells. There are two main pathways for the synthesis of phosphatidylcholine: the CDP-choline pathway present in all eukaryotes and the phosphatidylethanolamine methylation pathway present in mammalian hepatocytes and some single celled eukaryotes, including
J Vionnet et al.
Glycobiology, 9(5), 481-487 (1999-04-20)
CMP-beta-N-acetylneuraminic acid (CMP-neuNAc) is the substrate for the sialylation of glycoconjugates by sialyltransferases in microbes and higher eukaryotes. CMP-neuNAc synthetase catalyzes the formation of this substrate, CMP-neuNAc, from CTP and neuNAc. In this report we describe the purification of CMP-neuNAc
Selective fluorometric detection of pyrophosphate and stringent alarmone with copper (II)-2, 6-bis (2-benzimidazolyl) pyridine complex
Zhao XJ and Huang CZ
Biosensors And Bioelectronics, 30(1), 282-286 (2011)
Ratiometric Detection of Adenosine-5?-triphosphate (ATP) and Cytidine-5?-triphosphate (CTP) with a Fluorescent Spider-Like Receptor in Water
Gupta AK, et al.
European Journal of Organic Chemistry, 2015(1), 122-129 (2015)
A molecular logic gate for the highly selective recognition of pyrophosphate with a hypocrellin A-Zn (II) complex
Zhao X and Huang CZ
Analyst, 135(11), 2853-2857 (2010)
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