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Merck
CN

30089

L-半胱氨酸

≥98.5% (RT), suitable for HPLC, BioUltra

别名:

(R)-2-氨基-3-巯基丙酸

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关于此项目

线性分子式:
HSCH2CH(NH2)CO2H
化学文摘社编号:
分子量:
121.16
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-158-2
MDL number:
Beilstein/REAXYS Number:
1721408
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产品名称

L-半胱氨酸, BioUltra, ≥98.5% (RT)

Quality Level

SMILES string

N[C@@H](CS)C(O)=O

InChI key

XUJNEKJLAYXESH-REOHCLBHSA-N

InChI

1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1

product line

BioUltra

assay

≥98.5% (RT)

form

powder or crystals

optical activity

[α]20/D +8.0±0.5°, c = 5% in 5 M HCl

technique(s)

HPLC: suitable

impurities

insoluble matter, passes filter test
≤0.5% foreign amino acids

ign. residue

≤0.05% (as SO4)

loss

≤0.05% loss on drying, 20 °C (HV)

color

white

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤500 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in 1 M HCl

UV absorption

λ: 260 nm Amax: 1.5
λ: 280 nm Amax: 0.2

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Application

L-半胱氨酸已用于抗体接枝过程中未反应的马来酰亚胺的淬灭。也用于制备亚硝基半胱氨酸贮备液,该贮备液用于诱导 S-亚硝基化,以实现可逆的半胱氨酸修饰。

Biochem/physiol Actions

NMDA 谷氨酸受体激动剂。
半胱氨酸是一种功能性氨基酸,调节生长、繁殖、维持和免疫的代谢。半胱氨酸提供蛋白质中的二硫键。与硫的转运直接相关。牛磺酸是半胱氨酸的代谢产物,可作为抗氧化剂控制细胞氧化还原状态。半胱氨酸参与作为信号分子的硫化氢的形成。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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商品

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

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