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About This Item
经验公式（希尔记法）:
C24H39NaO5 · xH2O
CAS号:
分子量:
430.55 (anhydrous basis)
Beilstein:
3582354
EC 号:
MDL编号:
UNSPSC代码:
12161900
PubChem化学物质编号:
NACRES:
NA.25
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描述
anionic
质量水平
方案
≥97.0% (dried material, NT)
表单
powder
旋光性
[α]20/D +36±2°, c = 0.6% in ethanol (dry matter)
分子量
micellar avg mol wt 900-1300
聚集数
2-3
缺失
≤5% loss on drying
CMC
9-15 mM (20-25°C)
溶解性
H2O: 0.1 M
H2O: 100 mg/mL
HLB
18
SMILES字符串
O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
InChI
1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChI key
MUVVIYFKOVLQHL-RCVKHMDESA-M
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一般描述
水合胆酸钠是一种生物表面活性剂，可作为水溶液中的还原剂。
水合胆酸钠是一种非变性阴离子洗涤剂。
应用
- 经皮给药的优化：应用于超弹性纳米囊泡配方中的水合胆酸钠可提高地夫可特（deflazacort）的生物利用度和抗炎功效，展现了其在经皮给药系统中的潜力，可用于诊断目的（Ali et al., 2021）。
- 用于IVD的纳米载体配方：该研究利用水合胆酸钠对胆汁体（bilosome）进行表面改性，其可作为杂化化合物的功能性和生物相容性纳米载体，该方法适用于创新IVD试剂的设计（Waglewska et al., 2020）。
- 用于皮肤给药的体外诊断试剂配方：水合胆酸钠在用于递送抗氧化剂的纳米传递体开发中发挥了重要作用，研究显示了其在创造具有抗氧化和抗衰老作用的皮肤应用诊断试剂中的作用（Avadhani et al., 2017）。
- 纳米技术中的分级和分离技术：水合胆酸钠显示了亲和力介导的分级顺序逆转（sorting order reversal）特性，它在密度梯度超速离心技术中至关重要，研究突显了其在诊断分析材料的精确分级和制备中的用途（Jang et al., 2016）
危险声明
预防措施声明
危险分类
Aquatic Chronic 3
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Dietary plant protein is well known to reduce serum cholesterol levels. Rice bran is a by-product of rice milling and is a good source of protein. The present study examined whether feeding rats a high-cholesterol diet containing 10% rice bran
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Royal jelly (RJ) intake lowers serum cholesterol levels in animals and humans, but the active component in RJ that lowers serum cholesterol level and its molecular mechanism are unclear. In this study, we set out to identify the bile acid-binding
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Transdermal administration of clonazepam, a poorly water-soluble benzodiazepine, is an interesting strategy for overcoming the drawbacks of its oral administration. With this aim, two nano-carrier formulations, based on ultra-deformable liposomes and microemulsions, have been developed to favour clonazepam transdermal delivery.
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