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24368C

EX-CELL^® Advanced CHO Feed 1 (不含葡萄糖)

Name: EX-CELL<SUP>®</SUP> Advanced CHO Feed 1 (不含葡萄糖)
Brand: SIGMA

制药生产

别名:

EX-CELL^® Advanced CHO Feed 1

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About This Item

UNSPSC代码:

12352200

NACRES:

NA.71

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SAFC

14366C

EX-CELL^® Advanced CHO Fed-batch培养基

SAFC

24366C

EX-CELL^® Advanced CHO Fed-batch培养基

SAFC

14365C

EX-CELL^® CD CHO Fusion

SAFC

24367C

EX-CELL^® Advanced CHO Feed 1 (含葡萄糖)

SAFC

59920C

EX-CELL^®止泡剂

Sigma-Aldrich

G8769

D -(+)-葡萄糖溶液

Sigma-Aldrich

D2650

二甲基亚砜

SAFC

1.03796

Cellvento^® 4Feed COMP

SAFC

24365C

EX-CELL^® CD CHO Fusion

Sigma-Aldrich

G7021

D -(+)-葡萄糖

产品线

EX-CELL^®

质量水平

500

表单

dry powder

技术

cell culture | mammalian: suitable (suspension)

运输

ambient

储存温度

2-8°C

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一般描述

EX-CELL^® Advanced CHO Feed 1 (不含葡萄糖)化学成分明确且不含有动物来源成分。该补料用于分批补料平台，可与EX-CELL^® Advanced CHO 分批补料培养基（14366C或24366C）一起使用。来自SAFC的最新平台经过特别开发设计，用于维持分批补料培养物中各种中国仓鼠卵巢（CHO）细胞的生长和生产，同时可灵活调节蛋白质的质量属性。这种实时分批补料平台采用多变量分析策略开发，以确定配方成分影响关键过程和产品属性（如滴度、褶皱膨胀（fold expansion）、受体表达、和T糖基化）的相关性。该平台不含次黄嘌呤和胸苷、 L-谷氨酰胺、酚红或2-巯基乙醇（2-ME）。

联系

提交EX-CELL Advanced CHO Fed-batch申请表以与SAFC代表取得联系。

数量

配制成每升培养基含64.1克粉末。

法律信息

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

14366C

EX-CELL^® Advanced CHO Fed-batch培养基, liquid

象形图

GHS05,GHS07

警示用语：

Danger

危险声明

H315,H317,H318

预防措施声明

P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338

危险分类

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

动植物来源培养基

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分析证书(COA)

Lot/Batch Number

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Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics.

Pao-Chun Lin et al.

mAbs, 11(5), 965-976 (2019-05-03)

Chinese hamster ovary (CHO) cells are the biopharmaceutical industry's primary means of manufacturing therapeutic proteins, including monoclonal antibodies. The major challenge in cell line development for the production of recombinant biopharmaceuticals lies in generating and isolating rare high-producing stable clones

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EX-CELL® Advanced™ CHO Fed-Batch System – Bioprocessing Technology Institute, Singapore Case Study

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Improving Fed-batch Yields in Upstream Bioprocessing

Our step-by-step guide to optimizing media and feed combinations for upstream bioprocessing.

Establishing the First GMP Guideline for Cell Culture Media

Cell culture media are vital for bioprocessing therapeutics. This page describes the central role of our organization in authoring purpose-built GMP for cell culture media.

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